1,4- Addition of diazomethane to a heterodiene: a direct preparation of the oxazolic ring
The reaction of naphthoquinone-oximes (3) and (4) with diazomethane yields directly, in one step, the oxazoles (5) and (6), respectively.A reação das naphthoquinona-oximas (3) e (4) com diazometano fornece diretamente, em uma etapa, os oxazóis (5) e (6),
Flávio da S. Emery +9 more
doaj +1 more source
Generation of superoxide and singlet oxygen from α-tocopherolquinone and analogues. [PDF]
Three potential routes to generation of reactive oxygen species from a tocopherolquinone have been identified. The quinone of the water-soluble vitamin E analogue Trolox C (Trol-Q) is reduced by hydrated electron and isopropanol a hydroxyalkyl radical ...
Bisby, RH +4 more
core +1 more source
Microbial biofilms readily form on many surfaces in nature including plant surfaces. In order to coordinate the formation of these biofilms, microorganisms use a cell-to-cell communication system called quorum sensing (QS).
Chieu Anh Kim Ta, John Thor Arnason
doaj +1 more source
A novel quinone: Quinone methide isomerase generates quinone methides in insect cuticle
Insoluble cuticle‐bound enzyme(s) of Manduca sexta pharate pupae, which is known to convert N‐acetyldopamine to N‐acetylnorepinephrine through the intermediate formation of quinone methide, also converted exogenously supplied N‐acetyldopamine quinone to N‐acetylnorepinephrine.
Saul, Steven, Sugumaran, Manickam
openaire +2 more sources
Microsomal superoxide anion production and NADPH-oxidation in a series of 22 aziridinylbenzoquinones [PDF]
Several 2,5-bis(1-aziridinyl)-1,4-benzoquinones (BABQs) can be activated to alkylating species by reduction of the quinone moiety. On the other hand, cytotoxicity of these compounds can be induced by redox cycling.
Koster, Andries Sj. +3 more
core +3 more sources
Recently, the well-known geographically wide distribution of sporotrichosis in Brazil, combined with the difficulties of effective domestic feline treatment, has emphasized the pressing need for new therapeutic alternatives.
Lais Cavalcanti dos Santos Velasco de Souza +12 more
doaj +1 more source
Alcohol drinking and mammary cancer: Pathogenesis and potential dietary preventive alternatives [PDF]
Alcohol consumption is associated with an increased risk of breast cancer, increasing linearly even with a moderate consumption and irrespectively of the type of alcoholic beverage.
Castro, Gerardo Daniel +1 more
core +1 more source
Alkylamino and aralkylamino derivatives of avarone and its mimetic as selective agents against non-small cell lung cancer cells, their antibacterial and antifungal potential [PDF]
In this paper, the synthesis of fourteen alkylamino and arylamino derivatives of sesquiterpene quinone avarone and its model compound tert-butylquinone is described.
Jeremić Marko +6 more
doaj +1 more source
Mechanistic Insights into Electronic Current Flow through Quinone Devices
Molecular switches based on functionalized graphene nanoribbons (GNRs) are of great interest in the development of nanoelectronics. In experiment, it was found that a significant difference in the conductance of an anthraquinone derivative can be ...
Lawrence Conrad +3 more
doaj +1 more source
Reductive activation of potential antitumor bis(aziridinyl)benzoquinones by xanthine oxidase: Competition between oxygen reduction and quinone reduction [PDF]
The reduction of a series of 2,5-bis(1-aziridinyl)-1,4-benzoquinone (BABQ) derivatives with various 3,6 substituents by the enzyme xanthine oxidase has been studied.
Janssen, L.H.M. +5 more
core +3 more sources

