Results 1 to 10 of about 29,559 (250)

An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable Alumina-Supported Heteropolyoxometalates [PDF]

open access: goldThe Scientific World Journal, 2012
We report a suitable quinoxaline synthesis using molybdophosphovanadates supported on commercial alumina cylinders as catalysts. These catalysts were prepared by incipient wetness impregnation.
Diego M. Ruiz   +4 more
doaj   +2 more sources

Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold

open access: yesMolecules, 2021
A quinoxaline scaffold exhibits various bioactivities in pharmacotherapeutic interests. In this research, twelve quinoxaline derivatives were synthesized and evaluated as new acetylcholinesterase inhibitors.
Paptawan Suwanhom   +5 more
doaj   +2 more sources

Quinoxaline Moiety: A Potential Scaffold against Mycobacterium tuberculosis

open access: yesMolecules, 2021
Background. The past decades have seen numerous efforts to develop new antitubercular agents. Currently, the available regimens are lengthy, only partially effective, and associated with high rates of adverse events. The challenge is therefore to develop
Marc Montana   +3 more
doaj   +2 more sources

2-(4-Chloroanilino)quinoxaline [PDF]

open access: goldActa Crystallographica Section E Structure Reports Online, 2008
There are two mol-ecules in the asymmetric unit of the title compound, C(14)H(10)ClN(3), with dihedral angles of 5.11 (10) and 13.61 (10)° between the aromatic ring systems. In the crystal structure, mol-ecules are linked by N-H⋯N hydrogen bonds, resulting in chains propagating in [010].
Azila Idris   +4 more
openalex   +5 more sources

Induction of Cell Death in Human A549 Cells Using 3-(Quinoxaline-3-yl) Prop-2-ynyl Methanosulphonate and 3-(Quinoxaline-3-yl) Prop-2-yn-1-ol

open access: yesMolecules, 2019
Despite major advancements in the development of various chemotherapeutic agents, treatment for lung cancer remains costly, ineffective, toxic to normal non-cancerous cells, and still hampered by a high level of remissions.
Mixo Aunny Sibiya   +5 more
doaj   +2 more sources

Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br): a green and neutral reaction media for the efficient, catalyst-free synthesis of quinoxaline derivatives [PDF]

open access: diamondJournal of the Serbian Chemical Society, 2010
Quinoxaline derivatives were produced in excellent yields and short reaction times via the condensation of 1,2-diamines with 1,2-diketones in the neutral ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under catalyst-free and microwave ...
MAASOOMEH KHEDRI   +9 more
doaj   +3 more sources

Synthesis and biological activity of some heterocyclic compounds containing quinoxaline and coumarin moieties [PDF]

open access: yesJournal of the Serbian Chemical Society, 2000
2,3-Dichloroquinoxaline (2) condensed with 7,8-dihydroxy-4-methylcoumarin to give the 1,4-dioxane derivative 4. 2.3-Dichloroquinoxaline (2) reacted with 4-hydroxycoumarin, 7-hydroxy-4-methylcoumarin and acyl hydrazide 13 to give either the 2,3 ...
M. E. ABD EL-FATTAH, I. M. EL-DEEN
doaj   +2 more sources

Analgesic and anti-inflammatory activity of quinoxaline derivatives: Design synthesis and characterization

open access: yesResults in Chemistry, 2023
Medicinal chemistry is a basic science that involves identification, synthesis and development of new drugs for therapeutic use. Biological importance of heterocycles makes them more crucial in pharmaceutical industries.In this work heterocyclics like ...
Geethavani Meka, Ramakrishna Chintakunta
doaj   +1 more source

Quinoxaline-2-carbonitrile [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2009
In the title compound, C9H5N3, the quinoxaline ring is essentially planar, with a maximum deviation of 0.012 (1) Å. Short inter­molecular distances between the centroids of the 2,3-dihydro­pyrazine and benzene rings [3.6490 (5) Å] indicate the existence of π⋯π inter­actions.
Hoong‐Kun Fun   +4 more
openaire   +3 more sources

A High-Throughput Screening Method for Determining the Optimized Synthesis Conditions of Quinoxaline Derivatives Using Microdroplet Reaction

open access: yesFrontiers in Chemistry, 2020
Quinoxaline derivatives demonstrate many distinguished chemical, biological, and physical properties and have a wide application in dyes, electroluminescent material, organic semiconductors, biological agents, etc.
Yanmei Yang   +8 more
doaj   +1 more source

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