Results 191 to 200 of about 29,559 (250)

Current status of quinoxaline and quinoxaline 1,4‐di‐N‐oxides derivatives as potential antiparasitic agents

Chemical Biology and Drug Design, 2021
Parasitic diseases are a public health problem, especially in developing countries where millions of people are affected every year. Current treatments have several drawbacks: emerging resistance to the existing drugs, lack of efficacy, and toxic side ...
Jacqueline Soto-Sánchez, J. D. Ospina‐Villa   +1 more
semanticscholar   +1 more source

Recent advances in the synthesis and reactivity of quinoxaline

, 2021
Quinoxaline has become a subject of extensive research due to its emergence as an important chemical moiety possessing a wide range of physicochemical and biological activities.
Gauravi Yashwantrao, S. Saha
semanticscholar   +1 more source

Manganese(I)-Catalyzed Sustainable Synthesis of Quinoxaline and Quinazoline Derivatives with the Liberation of Dihydrogen.

Journal of Organic Chemistry, 2020
Direct synthesis of N-heterocycles via the acceptorless dehydrogenative coupling (ADC) is very challenging and scarcely reported under 3d-transition metal catalysis.
Akash Mondal, M. Sahoo, M. Subaramanian, E. Balaraman   +3 more
semanticscholar   +1 more source

Quinoxalines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
S. Gobec, U. Urleb
openaire   +1 more source

Quinoxaline-Bridged Porphyrinoids

Journal of the American Chemical Society, 2002
Quinoxaline-bridged porphyrinoids (3), the first macrocycles containing dipyrrolylquinoxaline (DPQ, 1) subunits, were synthesized from the condensation of the diformyl-substituted DPQ derivatives (2) and 1,8-diaminoanthracene. The resulting structures were confirmed by X-ray analyses, which showed encapsulation of CHCl(3) molecules within the columnar ...
Jonathan L, Sessler, Hiromitsu, Maeda, Toshihisa, Mizuno, Vincent M, Lynch, Hiroyuki, Furuta   +4 more
openaire   +2 more sources

Explore new quinoxaline pharmacophore tethered sulfonamide fragments as in vitro α‐glucosidase, α‐amylase, and acetylcholinesterase inhibitors with ADMET and molecular modeling simulation

Drug development research (Print)
A new series of quinoxaline‐sulfonamide derivatives 3–12 were synthesized using fragment‐based drug design by reaction of quinoxaline sulfonyl chloride (QSC) with different amines and hydrazines. The quinoxaline‐sulfonamide derivatives were evaluated for
A. Ragab, Mohamed A Salem, Y. Ammar, W. Aboulthana, M. H. Helal, Moustafa S. Abusaif   +5 more
semanticscholar   +1 more source

Synthesis, EGFR-TK inhibition and anticancer activity of new quinoxaline derivatives

, 2020
Ethyl 4-substituted-3-oxo-quinoxaline-2-carboxylates 3–5 were obtained via alkylation of ethyl 3-oxo-3,4-dihydroquinoxaline-2-carboxylate (1). Compound 1 was heterocyclized using hydrazines, ethylenediamine, and ethanolamine to give pyrazoloquinoxalines ...
Eman A. Ahmed, M. Mohamed, A. Omran, H. Salah   +3 more
semanticscholar   +1 more source

Structures of quinoxaline antibiotics

Acta Crystallographica Section B Structural Science, 1995
The crystal structures of three quinoxaline antibiotics-echinomycin 2QN, triostin C and the C222(1) form of triostin A--have been determined, and the structure of the P2(1)2(1)2(1) form of triostin A has been re-refined against our previously reported data. The molecular conformations are compared with those deduced from NMR data and those reported for
G M, Sheldrick, A, Heine, K, Schmidt-Bäse, E, Pohl, P G, Jones, E, Paulus, M J, Waring   +6 more
openaire   +2 more sources

Synthesis, Antibacterial Activity and Molecular Docking Study of a Series of 1,3-Oxazole-Quinoxaline Amine Hybrids

Polycyclic aromatic compounds (Print), 2020
A series of 1,3-oxazole-quinoxaline amine hybrids were prepared successfully through a copper-free Sonogashira coupling followed by heteroannulation in a one-pot process.
Ali Keivanloo, Sima Abbaspour, S. Sepehri, M. Bakherad   +3 more
semanticscholar   +1 more source

Introducing Fluorine and Sulfur Atoms into Quinoxaline-Based p-type Polymers To Gradually Improve the Performance of Fullerene-Free Organic Solar Cells.

ACS Macro Letters, 2019
Three quinoxaline-based "D-π-A" conjugated polymers, named as PE61, PE62, and PE63, are utilized to investigate the effect of introducing fluorine and sulfur atoms into the thiophene side chains on the photovoltaic performance when paired with a ...
Jing Yang, Peiqing Cong, Lie Chen, Xiaochen Wang, Jianfeng Li, Ailing Tang, Bao Zhang, Yanfang Geng, Erjun Zhou   +8 more
semanticscholar   +1 more source