Results 51 to 60 of about 29,559 (250)

Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases

open access: yesBeilstein Journal of Organic Chemistry, 2018
Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.
Svetlana O. Kasatkina   +4 more
doaj   +1 more source

New quinoxaline derivative as a green corrosion inhibitor for mild steel in mild acidic medium: Electrochemical and theoretical studies

open access: yesInternational Journal of Corrosion and Scale Inhibition, 2019
The influence of new quinoxaline derivative namely ( E )-3-(4-methylstyryl)quinoxalin-2(1 H )-one (QNMS) on the corrosion of mild steel in 1 M HCl was studied using using Tafel polarization and electrochemical impedance spectroscopy.
T. Laabaissi   +9 more
semanticscholar   +1 more source

Beyond Silicon: Toward Sustainable, NIR‐II, and Conformable Organic Photodiodes

open access: yesAdvanced Energy Materials, EarlyView.
In this perspective, a strategic shift in organic photodetector (OPD) research is proposed: instead of the incremental advances in silicon's stronghold arena, the most impactful future for OPDs lies in addressing silicon's intrinsic limitations, i.e., detection in the longer wavelength range above silicon's coverage (>1100 nm, termed as near infrared ...
Hrisheekesh Thachoth Chandran   +7 more
wiley   +1 more source

2-(4-Bromophenyl)quinoxaline

open access: yesActa Crystallographica Section E Structure Reports Online, 2010
In the title compound, C(14)H(9)BrN(2), the benzene and quinoxaline rings are almost coplanar [r.m.s. deviation = 0.0285 (3) Å and dihedral angle = 2.1 (2)°].
Zhi-jian Wang   +4 more
openaire   +3 more sources

Conformational Trajectory of the Molecular Chameleon Grazoprevir from Formulation to Target‐Bound

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Macrocycles represent a promising class of beyond‐rule‐of‐5 (bRo5) therapeutics, capable of targeting proteins traditionally considered undruggable by conventional small molecules. Macrocycles exhibit intrinsic flexibility and often display a “chameleon‐like” ability to adapt to their environment, thereby enhancing their oral bioavailability ...
Lianne H. E. Wieske   +5 more
wiley   +1 more source

New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

open access: yesMolecules, 2021
Proviral integration site for Moloney murine leukemia virus (Pim)-1/2 kinase overexpression has been identified in a variety of hematologic (e.g., multiple myeloma or acute myeloid leukemia (AML)) and solid (e.g., colorectal carcinoma) tumors, playing a ...
Bruno Oyallon   +13 more
doaj   +1 more source

2-(4-Fluorophenyl)quinoxaline

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
In the title compound, C14H9FN2, the dihedral angle between the benzene ring and the quinoxaline ring system is 22.2 (3)°. Any aromatic π–π stacking in the crystal must be very weak, with a minimum centroid–centroid separation of 3.995 (2) Å.
Cui-Ping Wang   +4 more
openaire   +3 more sources

Hole‐Selective Self‐Assembled Monolayers Overlaid on NiOx or PEDOT:PSS for Tin‐Based Perovskite Solar Cells – An Overview of Recent Characterization Methods

open access: yesChemistry – A European Journal, EarlyView.
Successfully applying self‐assembled monolayers with hole‐selectivity for lead‐free tin perovskite solar cells requires judicious investigation with appropriately powerful characterization methods, in addition to efforts in the development of new materials and processing.
Donghoon Song   +3 more
wiley   +1 more source

Synthesis and Characterization of Some New Quinoxalin-2(1H)one and 2-Methyl-3H-quinazolin-4-one Derivatives Targeting the Onset and Progression of CRC with SAR, Molecular Docking, and ADMET Analyses

open access: yesMolecules, 2021
The pathogenesis of colorectal cancer is a multifactorial process. Dysbiosis and the overexpression of COX-2 and LDHA are important effectors in the initiation and development of the disease through chromosomal instability, PGE2 biosynthesis, and ...
Nahed N. E. El-Sayed   +6 more
doaj   +1 more source

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

open access: yesChemistry – A European Journal, EarlyView.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez   +3 more
wiley   +1 more source

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