Results 61 to 70 of about 9,595 (171)

A Comparative Analysis of Maillard‐Derived α‐Dicarbonyl Compounds and Advanced Glycation End Products in Fresh, Wet, Kibble, and Freeze‐Dried Dog Foods

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Thermal processing of pet foods can lead to the formation of harmful Maillard reaction products (MRPs), which may compromise nutritional quality and pose health risks to companion animals. This study compared the levels of MRPs in 41 commercial dog foods, including fresh (n = 15), kibble (n = 13), wet (n = 10), freeze‐dried (n = 2), and cold ...
Tolgahan Kocadağlı, Ciara Clarke, Vural Gökmen   +2 more
wiley   +1 more source

Ethyl 1′′-benzyl-1′-methyl-2′′-oxodispiro[indeno[1,2-b]quinoxaline-11,3′-pyrrolidine-2′,3′′-indoline]-4′-carboxylate

Acta Crystallographica Section E, 2013
In the title compound, C36H30N4O3, the quinoxaline–indene system is roughly planar, with a maximum deviation from the mean plane of 0.218 Å for the C atom shared with the central pyrrolidine ring.
Piskala Subburaman Kannan, Srinu Lanka, Sathiah Thennarasu, Elumalai Govindan, Arunachalathevar SubbiahPandi   +4 more
doaj   +1 more source

Divergent Access to Fluorinated Pharmacons From Ethyl Trifluoropyruvate

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
Fluoro(oxo) functional group diversification is traditionally accomplished through either specialized reagents or nucleophilic trifluoromethylation. Herein is disclosed the use of commercially available building blocks for the synthesis of trifluoromethyl(hydroxy) esters.
Rifat N. Nabi, Ryan C. Kashatus, Kaden M. Joseph, Salina Zhang, Daniel K. Kim   +4 more
wiley   +1 more source

(4aR*,8aS*)-2,3-Diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline

Acta Crystallographica Section E, 2012
In the title compound, C20H20N2, the quinoxaline ring adopts a very distorted half-chair conformation [N=C—C=N = 22.7 (2)° for the nominally coplanar atoms] and the cyclohexane ring adopts a chair conformation.
W. Chen, K.-S. Tang, L.-Y. Fan
doaj   +1 more source

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley   +1 more source

Solution‐Processed Organic Photovoltaics: Fabrication Advances and Challenges

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights recent advances in organic photovoltaic (OPV) device fabrication, emphasizing how material selection, interface engineering, and scalable processing techniques shape device performance. It discusses progress in photoactive and charge transport layers, electrode optimization, and large‐area manufacturing, offering insights into ...
Kerui Liu, Chenyujie Zhu, Yuanyuan Jiang, Feng Liu, Xiaozhang Zhu   +4 more
wiley   +1 more source

Comparative Analysis of Intermediate and Advanced Maillard Reaction Products in Three Types of Commercial Edible Mushroom Products

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT In recent years, rising consumption of mushroom‐based foods has highlighted concerns over the formation of harmful Maillard reaction products (HMRPs) during thermal processing. However, limited information is available on the occurrence of intermediate and advanced HMRPs, such as α‐dicarbonyl compounds (α‐DCs) and advanced glycation end ...
Yong Li, Hua Li, Jialu Yan, Zhengli Wang, Jingyu Liu, Junlong Meng, Fatih Oz, Jie Chen, Maomao Zeng, Cuiping Feng   +9 more
wiley   +1 more source

A Selective MAP3K1 Inhibitor Facilitates Discovery of NPM1 as a Member of the Network

Molecules
The quinoxaline core is found in several biologically active compounds, with Erdafitinib being the first FDA-approved quinoxaline derivative that targets a kinase and exhibits anti-cancer properties.
Lidia Boghean, Sarbjit Singh, Kiran K. Mangalaparthi, Smitha Kizhake, Lelisse Umeta, Donn Wishka, Paul Grothaus, Akhilesh Pandey, Amarnath Natarajan   +8 more
doaj   +1 more source

Studies in Benzimidazo Thiazolo Quinoxalines and Benzimidazo Thiazino Quinoxalines

, 1970
Benzimidazo (2', 1': 2, 3) thiazolo (4, 5-b) quinoxalines and 7H-benzimidazo (1', 2': 4, 5) (1 : 4) thiazino (2, 3-b) quinoxalines have been synthesised by the condensations of 2-mercapto benzimidazoles with 2 : 3-dichloro quinoxalines and 2-(mercaptomethyl) benzimidazole with 2 : 3-dichloro quinoxalines respectively.
Simran Singh, Singh, Chanan, K. S. Narang   +2 more
openaire   +1 more source

Upcycling Agricultural By‐Product: Therapeutic Potential of Oriental Melon Stem (Cucumis melo var. makuwa) in Treating Obesity and Fatty Liver via Enhanced Thermogenesis

Food Frontiers, Volume 7, Issue 2, March 2026.
This study proposes the upcycling of oriental melon (Cucumis melo var. makuwa) stems, typically discarded as agricultural waste, into a bioactive extract with functional potential. CMSE ameliorates high‐fat‐diet‐induced obesity and fatty liver, contributing to the restoration of metabolic health by enhancing the expression of thermogenesis‐related ...
Myeong‐Jin Kim, Ji Yun Van, Su‐Yeon Park, Ji Young Hwang, Yerin Seong, Yeo Jin Park, Seokmin Lee, Bo‐mi Ryu, Joo Yun Jun, Won‐Kyo Jung, Bonggi Lee   +10 more
wiley   +1 more source