Results 111 to 120 of about 9,953 (212)

New opportunities for the synthesis of quinoxaline derivatives

Chimica Techno Acta, 2019
Convenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated.
Olga S. Koptyaeva, Yuriy A. Azev, Yuriy M. Shafran, Tatyana A. Pospelova, Oleg N. Chupakhin   +4 more
doaj   +1 more source

Heat‐Induced Toxicants: Sensory Appeal Distracts Consumers' Attention From Potential Toxicological Risks of Thermally Processed Foods

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
The central paradox of thermal processing of foods. (A) The application of heat (e.g., frying, baking, grilling) to food initiates complex chemical reactions, most notably the Maillard reaction and thermal degradation of protein, lipids, and carbohydrate. (B) These reactions create a desirable sensory experience characterized by enticing aromas, golden‐
Joachim Dotto Matondo, Abdulsudi Issa‐Zacharia   +1 more
wiley   +1 more source

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

ChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma, Fernando Rogério Pavan, Cesar Augusto Roque‐Borda   +2 more
wiley   +1 more source

Antioxidant Activity and Oxidation Products of 1,2,3,4- Tetrahydroquinoxalines in Peroxyl Radical Scavenging Reactions, Part I [PDF]

, 2005
This paper studies the antioxidant activity of 1,2,3,4-tetrahydroquinolines, 3,4-dihydro-2H-benzo[1,4]thiazines and 1,2,3,4-tetrahydroquinoxalines in the inhibition of the peroxidation of tetralin induced by an azo initiator.
Nishiyama Tomohiro, Oka Ryohei, Sakaguchi Tomoki, Sakata Toshifumi, Takahashi Masamitsu, Tanaka Daisuke   +5 more
core   +1 more source

Modular Donor‐Acceptor Diradicaloids Based on an Electron Deficient N‐Heteroacene Acceptor

Small, Volume 22, Issue 20, 7 April 2026.
This work presents a modular approach to donor‐acceptor‐donor (D‐A‐D) diradicaloids that show systematic evolution of their energy gaps, singlet‐triplet splittings, and diradical character (y). The correlation of (opto)electronic, spin, and magnetic properties with high‐fidelity theoretical investigations provides clear connections between the degree ...
Tanner L. Smith, Zhendian Zhang, Tanya A. Balandin, Paramasivam Mahalingam, Andrew H. Comstock, Anna M. Österholm, Michael K. Bowman, Molly M. Lockart, Guoxiang Hu, Jason D. Azoulay   +9 more
wiley   +1 more source

Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]

, 1986
The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R., Cox, O., Elo, Hannu, Kovacic, Peter, Lumme, Paavo, Ryan, Michael D.   +5 more
core   +1 more source

Synthesis of quinoxaline derivatives using different solvent systems, their potent antibacterial activities and molecular docking

Results in Chemistry
In this study, a new series of quinoxaline derivatives were synthesized by the reaction of 2,3-dichloroquinoxaline with aromatic thiols, leading to the formation of 2,3-bis(arylthiol)quinoxaline, 4-chloro-12H-quinoxalino[2,3-b]1,4-benzothiazine and 5 ...
Hena Khatoon, Emilia Abdul Malek, Siti Munirah Mohd Faudzi, Tabrej Khan, Omar Shabbir Ahmed   +4 more
doaj   +1 more source

Mft1, identified from a genome-wide screen of the yeast haploid mutants, mediates cell cycle arrest to counteract quinoxaline-induced toxicity

Frontiers in Genetics
Quinoxaline is a heterocyclic compound with a two-membered ring structure that undergoes redox cycling to produce toxic free radicals. It has antiviral, antibacterial, antifungal, and antitumor activities.
Abdallah Alhaj Sulaiman, Dana E. Al-Ansari, Dana E. Al-Ansari, Reem Ali, Mustapha Aouida, Dindial Ramotar   +5 more
doaj   +1 more source

A comprehensive approach utilizing quantum machine learning in the study of corrosion inhibition on quinoxaline compounds

Artificial Intelligence Chemistry
In this investigation, a quantitative structure-property relationship (QSPR) model coupled with a quantum neural network (QNN) was used to explore the corrosion inhibition efficiency (CIE) of quinoxaline compounds. Integrating quantum chemical properties
Muhamad Akrom, Supriadi Rustad, Hermawan Kresno Dipojono, Ryo Maezono   +3 more
doaj   +1 more source

Biological activity of quinoxaline derivatives.

Veterinaria i kormlenie, 2023
A.I. Klimenko, V.V. Chekrysheva, A.A. Zubenko, L.N. Fetisov, A.E. Svyatogorova, E.N. Avagyan   +5 more
openaire   +1 more source