Results 141 to 150 of about 3,612 (183)
Some of the next articles are maybe not open access.
Quinoxaline Derivatives: Synthesis and Biological Significance
2023Quinoxaline is a well-known and important nitrogen-containing heterocyclic compound with a complex ring consisting of a benzene ring and a pyrazine ring. Different modified quinoxalines and their derivatives with various functional groups are an important part of biological science, and important research projects are introduced in this course.
Ridhima Chauhan +2 more
openaire +1 more source
Ugi-Smiles Access to Quinoxaline Derivatives
HETEROCYCLES, 2007Two different Ugi-Smiles post-condensations strategies have been used for new three and four-component formation of quinoxaline scaffolds. In the first approach, a one-pot hydrogenation-cyclization affords the heterocycle with loss of the initial isocyanide moiety.
Oble, Julie +3 more
openaire +1 more source
Electrochemical behavior of conjugated quinoxaline derivatives
Journal of Electroanalytical Chemistry, 2004The electrochemical behavior of three kinds of conjugated quinoxaline derivatives has been studied in 95% DMF + water mixed acidic media. These compounds are electrochemically reduced by one, two or three steps which are equal to the number of pyrazine rings in the individual molecules.
R.Wang +7 more
openaire +1 more source
Palladium-catalyzed synthesis of quinoxaline derivatives
Tetrahedron, 2008Abstract A palladium-catalyzed reductive N-heteroannulation of enamines derived from 2-nitrobenzenamines forming mixtures of 1,2-dihydroquinoxalines and 3,4-dihydroquinoxalin-2-ones is described. The reactions are performed using bis(dibenzylideneacetone)palladium(0), 1,3-bis(diphenylphosphino)propane, and 1,10-phenanthroline in DMF under 6 atm of ...
Jeffery M. Wallace +4 more
openaire +1 more source
CRYSTALLINE QUINOXALINE DERIVATIVE
2000Crystalline forms of (S)-2-ethyl-7-fluoro-3-oxo-3,4-dihydro-2H-quinoxaline-1-carboxylic acid isopropyl ester, also known as (S)-1-methylethyl 2-ethyl-7-fluoro-3,4-dihydro-3-oxo-1(2H)-quinoxaline carboxylate, the compound of formula (I), process for their preparation, pharmaceutical formulations thereof and their use in therapy.
GLAXO GROUP LTD +3 more
openaire +1 more source
Monomer and polymer quinoxaline derivatives for cationic recognition
Analytical and Bioanalytical Chemistry, 2003Monomeric and polymeric 5-nitroquinoxaline derivatives disubstituted in the 2 and 3 positions with 2-pyrrolyl (A), 2-furyl (B) and 2-thienyl (C) groups were prepared and characterized. The substituted 5-nitroquinoxalines were used as active components in poly(vinyl chloride)-membrane and electropolymerized electrodes that were then tested as possible ...
H, Breznová +5 more
openaire +2 more sources
Antitumoral activity of quinoxaline derivatives: A systematic review
European Journal of Medicinal Chemistry, 2019Cancer is a leading cause of death and a major health problem worldwide. While many effective anticancer agents are available, the majority of drugs currently on the market are not specific, raising issues like the common side effects of chemotherapy. However, recent research hold promise for the development of more efficient and safer anticancer drugs.
Montana, M. +3 more
openaire +3 more sources
Quinoxaline derivatives as potential antitrypanosomal and antileishmanial agents
Bioorganic & Medicinal Chemistry, 2018Continuous efforts have been made to discover new drugs for the treatment of Chagas' disease, human African trypanosomiasis, and leishmaniasis. We have previously reported the synthesis and antileishmanial and antitrypanosomal (Y strain) properties of 2,3-disubstituted quinoxalines. Considering their promising antiparasitic potential, the present study
Juliana Cogo +8 more
openaire +2 more sources
SYNTHESIS OF SOME DERIVATIVE QUINOXALINE
GEORGIAN SCIENTISTS, 2023Irma Jinikashvili, Badri Arzian
openaire +1 more source
QUINOXALINE DERIVATIVES AS ANTITUBERCULOSIS AGENTS
2014The invention refers to a new class of quinoxaline derivatives and pharmaceutical acceptable salts thereof, useful as anti tuberculosis agents, in particular in the treatment of pathologies caused by Mycobacterium tuberculosis.
COSTI, Maria Paola +6 more
openaire +1 more source