Results 191 to 200 of about 9,953 (212)

Ugi-Smiles Access to Quinoxaline Derivatives

HETEROCYCLES, 2007
Two different Ugi-Smiles post-condensations strategies have been used for new three and four-component formation of quinoxaline scaffolds. In the first approach, a one-pot hydrogenation-cyclization affords the heterocycle with loss of the initial isocyanide moiety.
Oble, Julie, El Kaim, Laurent, Gizzi, Marion, Grimaud, Laurence   +3 more
openaire   +1 more source

Electrochemical behavior of conjugated quinoxaline derivatives

Journal of Electroanalytical Chemistry, 2004
The electrochemical behavior of three kinds of conjugated quinoxaline derivatives has been studied in 95% DMF + water mixed acidic media. These compounds are electrochemically reduced by one, two or three steps which are equal to the number of pyrazine rings in the individual molecules.
R.Wang, R.Ramaraj, T.Okajima, F.Kitamura, N.Matsumoto, T.Thiemann, S.Mataka, T.Ohsaka   +7 more
openaire   +1 more source

Palladium-catalyzed synthesis of quinoxaline derivatives

Tetrahedron, 2008
Abstract A palladium-catalyzed reductive N-heteroannulation of enamines derived from 2-nitrobenzenamines forming mixtures of 1,2-dihydroquinoxalines and 3,4-dihydroquinoxalin-2-ones is described. The reactions are performed using bis(dibenzylideneacetone)palladium(0), 1,3-bis(diphenylphosphino)propane, and 1,10-phenanthroline in DMF under 6 atm of ...
Jeffery M. Wallace, Björn C.G. Söderberg, Joaquín Tamariz, Novruz G. Akhmedov, Mathew T. Hurley   +4 more
openaire   +1 more source

CRYSTALLINE QUINOXALINE DERIVATIVE

2000
Crystalline forms of (S)-2-ethyl-7-fluoro-3-oxo-3,4-dihydro-2H-quinoxaline-1-carboxylic acid isopropyl ester, also known as (S)-1-methylethyl 2-ethyl-7-fluoro-3,4-dihydro-3-oxo-1(2H)-quinoxaline carboxylate, the compound of formula (I), process for their preparation, pharmaceutical formulations thereof and their use in therapy.
GLAXO GROUP LTD, MEADOWS JAMES DAVID, PINCOTT KIM MARISSA, SEAGER JOHN FREDERICK   +3 more
openaire   +1 more source

Monomer and polymer quinoxaline derivatives for cationic recognition

Analytical and Bioanalytical Chemistry, 2003
Monomeric and polymeric 5-nitroquinoxaline derivatives disubstituted in the 2 and 3 positions with 2-pyrrolyl (A), 2-furyl (B) and 2-thienyl (C) groups were prepared and characterized. The substituted 5-nitroquinoxalines were used as active components in poly(vinyl chloride)-membrane and electropolymerized electrodes that were then tested as possible ...
H, Breznová, R, Volf, V, Král, J L, Sessler, A C, Try, T V, Shishkanova   +5 more
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Antitumoral activity of quinoxaline derivatives: A systematic review

European Journal of Medicinal Chemistry, 2019
Cancer is a leading cause of death and a major health problem worldwide. While many effective anticancer agents are available, the majority of drugs currently on the market are not specific, raising issues like the common side effects of chemotherapy. However, recent research hold promise for the development of more efficient and safer anticancer drugs.
Montana, M., Mathias, F., Terme, T., Vanelle, P.   +3 more
openaire   +3 more sources

Quinoxaline derivatives as potential antitrypanosomal and antileishmanial agents

Bioorganic & Medicinal Chemistry, 2018
Continuous efforts have been made to discover new drugs for the treatment of Chagas' disease, human African trypanosomiasis, and leishmaniasis. We have previously reported the synthesis and antileishmanial and antitrypanosomal (Y strain) properties of 2,3-disubstituted quinoxalines. Considering their promising antiparasitic potential, the present study
Juliana Cogo, Juan Cantizani, Ignacio Cotillo, Diego Pereira Sangi, Arlene Gonçalves Corrêa, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, José Julio Martín, Celso Vataru Nakamura   +8 more
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SYNTHESIS OF SOME DERIVATIVE QUINOXALINE

GEORGIAN SCIENTISTS, 2023
Irma Jinikashvili, Badri Arzian
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QUINOXALINE DERIVATIVES AS ANTITUBERCULOSIS AGENTS

2014
The invention refers to a new class of quinoxaline derivatives and pharmaceutical acceptable salts thereof, useful as anti tuberculosis agents, in particular in the treatment of pathologies caused by Mycobacterium tuberculosis.
COSTI, Maria Paola, FERRARI, Stefania, SAXENA, PUNEET, VENTURELLI, Alberto, FARINA, Davide Salvatore Francesco, LUCIANI, Rosaria, GADUPUDI, RAMAKRISHNA   +6 more
openaire   +1 more source

Transition-metal quinoxaline complexes. Part III. Copper(II) derivatives with substituted quinoxalines

Journal of the Chemical Society A: Inorganic, Physical, Theoretical, 1966
Copper(II) halides form complexes of the type CuX2L2(L is 2,3-diphenyl- and 2-methyl-quinoxaline) and CuX2L (L is 2,3-dimethylquinoxaline) with substituted quinoxaline. The 2,3-diphenylquinoxaline complexes appear to be monomeric whereas the others are polymeric.
D. E. Billing, A. E. Underhill, D. M. Adams, D. M. Morris   +3 more
openaire   +1 more source