Results 81 to 90 of about 9,953 (212)

Compounds Containing 2,3‐Bis(phenylamino) Quinoxaline Exhibit Activity Against Methicillin‐Resistant Staphylococcus aureus, Enterococcus faecalis, and Their Biofilms

MicrobiologyOpen
Antimicrobial resistance remains a global issue, hindering the control of bacterial infections. This study examined the antimicrobial properties of 2,3‐N,N‐diphenyl quinoxaline derivatives against Gram‐positive, Gram‐negative, and Mycobacterium species ...
Gilda Padalino, Katrina Duggan, Luis A. J. Mur, Jean‐Yves Maillard, Andrea Brancale, Karl F. Hoffmann   +5 more
doaj   +1 more source

Fused-Ring Derivatives of Quinoxalines: Spectroscopic Characterization and Photoinduced Processes Investigated by EPR Spin Trapping Technique

Molecules, 2014
10-Ethyl-7-oxo-7,10-dihydropyrido[2,3-f]quinoxaline derivatives, synthesized as promising biologically/photobiologically active compounds were characterized by UV/vis, FT-IR and fluorescent spectroscopy.
Zuzana Barbieriková, Dana Dvoranová, Maroš Bella, Viktor Milata, Adriana Czímerová, Vlasta Brezová   +5 more
doaj   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Crystal Structure and Intramolecular Hydrogen Bonding of a Substituted Diaminoquinoxaline [PDF]

, 2009
A substituted diaminoquinoxaline, 2,3-diethyl-N5,N8-di(quinolin-8-yl)quinoxaline-5,8-diamine, was synthesized and characterized by a single-crystal X-ray diffraction study.
Kuwabara Junpei, Mori Hironori, 桑原 純平, 神原 貴樹, 神原 貴樹   +4 more
core   +1 more source

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

Cell Proliferation, EarlyView.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li, Wanxia Wang, Yuxin Zhou, Tao Zeng, Jian Liu, Yingjie Qing, Xuan Han   +6 more
wiley   +1 more source

Ion exchange membranes based upon crosslinked sulfonated polyethersulfone for electrochemical applications [PDF]

, 2013
Synthesis and characterization of new ion exchange membranes made from chlorosulfonated polyethersul- fone (SO2Cl-PES) crosslinked by polyaminated crosslinking reagents have been performed.
FAUVARQUE, J.F, MABROUK, Walid, MATOUSSI, F., OGIER, Lionel, SOLLOGOUB, Cyrille, VIDAL, Serge   +5 more
core   +6 more sources

An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024)

Results in Chemistry
Quinoxaline derivatives have garnered significant attention due to their wide-ranging therapeutic applications. Research from 2020 to 2024 has demonstrated their potent bioactivity across various domains, including anticancer, antimicrobial, antiviral ...
Aly M. Waseem, Ranya Mohammed Elmagzoub, Mervat Mohammed Mazhar Abdelgadir, Areej Al Bahir, N.S. Abd EL-Gawaad, Ahmed S. Abdel-Samea, Devendra Pratap Rao, Konstantinos Kossenas, Stefan Bräse, Hamada Hashem   +9 more
doaj   +1 more source

A Comparative Analysis of Maillard‐Derived α‐Dicarbonyl Compounds and Advanced Glycation End Products in Fresh, Wet, Kibble, and Freeze‐Dried Dog Foods

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Thermal processing of pet foods can lead to the formation of harmful Maillard reaction products (MRPs), which may compromise nutritional quality and pose health risks to companion animals. This study compared the levels of MRPs in 41 commercial dog foods, including fresh (n = 15), kibble (n = 13), wet (n = 10), freeze‐dried (n = 2), and cold ...
Tolgahan Kocadağlı, Ciara Clarke, Vural Gökmen   +2 more
wiley   +1 more source

Electrochromic properties of a poly(dithienylfuran) derivative featuring a redox-active dithiin unit [PDF]

, 2012
A teraryl monomer containing a 1,4-dithiin-furan central unit has been synthesised and characterised by single crystal X-ray crystallography. The di(thienyl)furan monomer 11 was successfully polymerised electrochemically and shown to possess a lower ...
Berridge, Rory, Coles, Simon J., Elmasly, Saadeldin E. T., Findlay, Neil J., Kanibolotsky, Alexander L., Kaur, Sandeep, Skabara, Peter, Wilson, Claire   +7 more
core   +1 more source

Quinoxaline 1,4-di-N-oxide Derivatives as New Antinocardial Agents

Molecules
Mycetoma is currently considered as a neglected tropical disease. The incidence of mycetoma is unknown but most of the worldwide cases are present in the “mycetoma belt” including countries like Mexico, India, Senegal, and others.
Isidro Palos, Alonzo González-González, Alma D. Paz-González, José C. Espinoza-Hicks, Debasish Bandyopadhyay, Norma Paniagua-Castro, Marlene S. Galeana-Salazar, Jorge Ismael Castañeda-Sánchez, Julieta Luna-Herrera, Gildardo Rivera   +9 more
doaj   +1 more source