Results 1 to 10 of about 14,380 (267)

Protocol for stereodivergent asymmetric hydrogenation of quinoxalines [PDF]

open access: yesSTAR Protocols, 2023
Summary: Chiral 1,2,3,4-tetrahydroquinoxalines are ubiquitous in natural products and bioactive molecules. Herein, we disclose a protocol for stereodivergent asymmetric hydrogenation of disubstituted quinoxalines for the preparation of both cis- and ...
Mingyang Wang, Chenguang Liu, Qiang Liu
doaj   +2 more sources

Synthesis of Functionalized 3H-pyrrolo-[1,2,3-de] Quinoxalines via Gold-Catalyzed Intramolecular Hydroamination of Alkynes [PDF]

open access: yesMolecules, 2023
A gold-catalyzed protocol to obtain functionalized 3H-pyrrolo [1,2,3-de] quinoxalines from suitable substituted N-alkynyl indoles has been proposed. The mild reaction conditions were revealed to be compatible with different functional groups, including ...
Antonia Iazzetti   +5 more
doaj   +2 more sources

Quinoxaline derivatives as attractive electron-transporting materials [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2023
This review article provides a comprehensive overview of recent advancements in electron transport materials derived from quinoxaline, along with their applications in various electronic devices. We focus on their utilization in organic solar cells (OSCs)
Zeeshan Abid   +5 more
doaj   +2 more sources

Benzylic C–H Oxidation: Recent Advances and Applications in Heterocyclic Synthesis [PDF]

open access: yesMolecules
Benzylic C–H oxidation to form carbonyl compounds, such as ketones, is a fundamental transformation in organic synthesis as it allows for the preparation of versatile intermediates.
Nonhlelo Majola, Vineet Jeena
doaj   +2 more sources

A Direct Method for Synthesis of Quinoxalines and Quinazolinones Using Epoxides as Alkyl Precursor [PDF]

open access: yesMolecules, 2023
An iodine-mediated one-pot synthesis of pyrrolo/indolo [1,2-a]quinoxalines and quinazolin-4-one via utilizing epoxides as alkyl precursors under metal-free conditions has been described.
Xueyan Lv   +5 more
doaj   +2 more sources

Anticancer, anti-inflammatory and analgesic activities of aminoalcohol-based quinoxaline small molecules [PDF]

open access: yesActa Cirúrgica Brasileira
Purpose: Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents.
Jannyely Moreira Neri   +9 more
doaj   +2 more sources

Synthesis and Structure-Chirality Relationship Analysis of Steroidal Quinoxalines to Design and Develop New Chiral Drugs

open access: yesChemistry, 2021
Of the utmost importance of chirality in organic compounds and drugs, the present work reports structure-chirality relationship of three steroidal quinoxalines, which were synthesised by condensing diaminobenzenes with cholestenone.
Rashid Mehmood   +4 more
doaj   +1 more source

A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines

open access: yesSynOpen, 2021
A highly efficient and catalyst-free protocol is reported for the synthesis of quinoxalines via the classical cyclocondensation reaction between aryldiamines and dicarbonyl compounds.
Vijayaragavan Elumalai, Jørn H. Hansen
doaj   +1 more source

Sustainable production of value-added N-heterocycles from biomass-derived carbohydrates via spontaneous self-engineering

open access: yesNational Science Open, 2023
: Synthetic N-heterocyclic compounds, such as quinoxalines, have shown a crucial role in pharmaceutical as well as food and dye industries. However, the traditional synthesis toward N-heterocycles relies on multistep energy and cost-intensive non ...
Yu Feng   +6 more
doaj   +1 more source

Green Synthesis of New Pyrrolo [1,2-a] quinoxalines as Antiproliferative Agents in GPER-expressing Breast Cancer Cells

open access: yesJournal of Chemistry, 2021
4,5-Dihydropyrrolo [1,2-a]quinoxalines are interesting druggable scaffolds, with multifaceted biological properties, including anticancer properties targeting the G protein-coupled estrogen receptor 1 (GPER).
Gabriele Carullo   +3 more
doaj   +1 more source

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