Nucleophilic Substitution on 2-Monosubstituted Quinoxalines Giving 2,3-Disubstituted Quinoxalines: Investigating the Effect of the 2-Substituent [PDF]
Molecules, 2016 An investigation on the effect of substituent at the 2-position of mono-substituted quinoxalines in the synthesis of di-substituted quinoxaline derivatives via nucleophilic substitution reactions, is reported.
Ndumiso Thamsanqa Ndlovu +1 more
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Protocol for stereodivergent asymmetric hydrogenation of quinoxalines [PDF]
STAR Protocols, 2023 Summary: Chiral 1,2,3,4-tetrahydroquinoxalines are ubiquitous in natural products and bioactive molecules. Herein, we disclose a protocol for stereodivergent asymmetric hydrogenation of disubstituted quinoxalines for the preparation of both cis- and ...
Mingyang Wang, Chenguang Liu, Qiang Liu
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Synthesis of Functionalized 3H-pyrrolo-[1,2,3-de] Quinoxalines via Gold-Catalyzed Intramolecular Hydroamination of Alkynes [PDF]
Molecules, 2023 A gold-catalyzed protocol to obtain functionalized 3H-pyrrolo [1,2,3-de] quinoxalines from suitable substituted N-alkynyl indoles has been proposed. The mild reaction conditions were revealed to be compatible with different functional groups, including ...
Antonia Iazzetti +5 more
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the very different redox behaviour of isoelectronic complexes with [PtCl2] and [AuCl2]+ [PDF]
, 2011 The new, potentially ambidentate heterocyclic ligand 2,3-bis(1-methylimidazol-2-yl)quinoxaline (bmiq) was obtained from 2,3-bis(1-methylimidazol-2-yl)glyoxal and 1,2-diaminobenzene.
Bulak, Ece +6 more
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An Efficient and Recyclable Nanoparticle-Supported Cobalt Catalyst for Quinoxaline Synthesis [PDF]
Molecules, 2015 The syntheses of quinoxalines derived from 1,2-diamine and 1,2-dicarbonyl compounds under mild reaction conditions was carried out using a nanoparticle-supported cobalt catalyst.
Fatemeh Rajabi +2 more
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Benzylic C–H Oxidation: Recent Advances and Applications in Heterocyclic Synthesis [PDF]
MoleculesBenzylic C–H oxidation to form carbonyl compounds, such as ketones, is a fundamental transformation in organic synthesis as it allows for the preparation of versatile intermediates.
Nonhlelo Majola, Vineet Jeena
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Anticancer, anti-inflammatory and analgesic activities of aminoalcohol-based quinoxaline small molecules [PDF]
Acta Cirúrgica BrasileiraPurpose: Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents.
Jannyely Moreira Neri +9 more
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Chemistry, 2021 Of the utmost importance of chirality in organic compounds and drugs, the present work reports structure-chirality relationship of three steroidal quinoxalines, which were synthesised by condensing diaminobenzenes with cholestenone.
Rashid Mehmood +4 more
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A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines
SynOpen, 2021 A highly efficient and catalyst-free protocol is reported for the synthesis of quinoxalines via the classical cyclocondensation reaction between aryldiamines and dicarbonyl compounds.
Vijayaragavan Elumalai, Jørn H. Hansen
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National Science Open, 2023 : Synthetic N-heterocyclic compounds, such as quinoxalines, have shown a crucial role in pharmaceutical as well as food and dye industries. However, the traditional synthesis toward N-heterocycles relies on multistep energy and cost-intensive non ...
Yu Feng +6 more
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