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Synthesis, molecular modelling, and biological evaluation of novel quinoxaline derivatives for treating type II diabetes. [PDF]
Alasmary FAS+6 more
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Alkynyl- and dialkynyl-quinoxalines. Synthesis of condensed quinoxalines
Journal of the Chemical Society, Perkin Transactions 1, 1980Condensation of 2-chloro- and 2,3-dichloro-quinoxalines with alk-1-ynes in the presence of bis(triphenylphosphine)palladium(II) dichloride and copper(I) iodide gives mono- and di-alkynylquinoxalines. Addition of amines to these products gives stable enamines; hydration gives 2′-oxoalkyl compounds which exist predominantly in the intramolecularly ...
M. Ismail Brohi, Donald E. Ames
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Structures of quinoxaline antibiotics
Acta Crystallographica Section B Structural Science, 1995The crystal structures of three quinoxaline antibiotics-echinomycin 2QN, triostin C and the C222(1) form of triostin A--have been determined, and the structure of the P2(1)2(1)2(1) form of triostin A has been re-refined against our previously reported data. The molecular conformations are compared with those deduced from NMR data and those reported for
Karen Schmidt-Bäse+6 more
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Quinoxaline-Bridged Porphyrinoids
Journal of the American Chemical Society, 2002Quinoxaline-bridged porphyrinoids (3), the first macrocycles containing dipyrrolylquinoxaline (DPQ, 1) subunits, were synthesized from the condensation of the diformyl-substituted DPQ derivatives (2) and 1,8-diaminoanthracene. The resulting structures were confirmed by X-ray analyses, which showed encapsulation of CHCl(3) molecules within the columnar ...
Hiroyuki Furuta+6 more
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Synthesis of fused quinoxalines
Mendeleev Communications, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Mikhail I. Kodess+4 more
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Pyrrolo[1,2-a]quinoxalines based on quinoxalines (Review)
Chemistry of Heterocyclic Compounds, 2010Published data on methods for the synthesis of pyrrolo[1,2-a]quinoxalines, based on derivatives of quinoxalines and also on compounds that are not initially derivatives of quinoxalines or pyrroles are summarized and classified.
Alexey A. Kalinin, Vakhid A. Mamedov
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Synthesis of Quinoxaline Analogues [PDF]
AbstractA straightforward synthesis of polycyclic title compounds is achieved by treatment of cyclic ketones with NBS followed by a direct one‐pot coupling with 1,2‐diaminoarenes.
Ru-Ting Hsu+3 more
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ChemInform Abstract: Pyrrolo[1,2‐a]quinoxalines Based on Quinoxalines
ChemInform, 2011AbstractReview: 65 refs.
A. A. Kalinin, V. A. Mamedov
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Quinoxalines Potential to Target Pathologies
Current Medicinal Chemistry, 2015The study of quinoxalines has increased immeasurably during the last two decades, due firstly to their relatively simple chemical synthesis, which has generated a vast variety of compounds with diverse structural modifications, and secondly, to the wide therapeutic potential and biological activities exhibited by this family of compounds.
Antonio Guirado+5 more
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