Results 41 to 50 of about 25,177 (318)
Beilstein Journal of Organic Chemistry, 2010 A series of polycyclic frameworks with fluorinated syn-facial quinoxaline sidewalls has been prepared as potential molecular tweezers for electron-rich guest compounds.
Markus Etzkorn +4 more
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Synthesis and Antimicrobial Activity of Some New Quinoxaline Derivatives
Pharmaceuticals, 2010 2-Chloro-3-methylquinoxaline was selected as a nucleus around which various molecular transformations were performed to obtain new compounds expected to possess optimized antimicrobial activity.
Ram Gopal Singhal +3 more
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Molecules, 2020 A new series of nitrogen and sulfur heterocyclic systems were efficiently synthesized by linking the following four rings: indole; 1,2,4-triazole; pyridazine; and quinoxaline hybrids. The strength of the acid that catalyzes the condensation of 4-amino-5-(
Ahmed T. A. Boraei +3 more
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Nucleic Acids Research, 2019 Conventional chemotherapy remains the primary treatment option for triple-negative breast cancer (TNBC). However, the current chemotherapeutic drugs have limited effects on TNBC, and often lead to serious side effects as well as drug resistance.
Ming-Hao Hu +3 more
semanticscholar +1 more source
Journal of Heterocyclic Chemistry, 1973 AbstractThe treatment of 3β‐hydroxy‐16α‐bromo‐5α‐androstan‐17‐one, 3β‐acetoxy‐16α‐bromo‐5‐androsten‐17‐one and 21‐bromo‐5‐pregnen‐3β‐ol‐20‐one with 4,5‐dimethyl‐o‐phenylenediamine gave substituted quinoxalines.Hydrolysis of 3β‐acetoxy‐5‐androsteno[16,17‐b]‐6′,7′‐dimethylquinoxaline produced the corresponding 3β‐hydroxy compound.
openaire +3 more sources
Molecules, 2019 We report the synthesis and relevant pharmacological properties of the quinoxalinetacrine (QT) hybrid QT78 in a project targeted to identify new non-hepatotoxic tacrine derivatives for Alzheimer’s disease therapy.
Eva Ramos +11 more
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An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable Alumina-Supported Heteropolyoxometalates [PDF]
, 2012 We report a suitable quinoxaline synthesis using molybdophosphovanadates supported on commercial alumina cylinders as catalysts. These catalysts were prepared by incipient wetness impregnation.
Autino, Juan C. +4 more
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ACS Catalysis, 2018 Base-metal catalyzed dehydrogenative self-coupling of 2-amino alcohols to selectively form functionalized 2,5-substituted pyrazine derivatives is presented.
P. Daw +5 more
semanticscholar +1 more source
Acta Crystallographica Section E Structure Reports Online, 2010 A new Z' = 1 crystal structure of quinoxaline (or 1,4-diaza-naphthalene), C(8)H(6)N(2), with one-fifth the volume of the earlier known Z' = 5 structure was obtained by means of an in situ cryocrystallization technique.
Ranganathan, Sathishkumar +3 more
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Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry
European Journal of Medicinal Chemistry Reports, 2022 Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities. In the
Suresh Kumar Suthar +4 more
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