One-Pot Morita-Baylis-Hillman/Allylic Substitution in Deep Eutectic Solvents: Access to γ-Hydroxy Derivatives via Sequential CC and CX (X = P, N, S, B, Si) Bond Formation. [PDF]
ChemSusChemSustainable one‐pot synthesis of functionalized γ‐hydroxy derivatives in deep eutectic solvents. A green, sequential CC/CX bond‐forming strategy enables diverse γ‐hydroxy derivatives via Morita–Baylis–Hillman and nucleophilic functionalization in ChCl/Gly deep eutectic solvent.
Ramos-Martín M +3 more
europepmc +2 more sources
Quinuclidine compounds differently act as agonists of Kenyon cell nicotinic acetylcholine receptors and induced distinct effect on insect ganglionic depolarizations [PDF]
, 2013 We have recently demonstrated that a new quinuclidine benzamide compound named LMA10203 acted as an agonist of insect nicotinic acetylcholine receptors.
D. Swale +6 more
core +3 more sources
Three-Dimensional Molecular Cartography of the Caribbean Reef-Building Coral Orbicella faveolata [PDF]
, 2021 All organisms host a diversity of associated viruses, bacteria, and protists, collectively defined as the holobiont. While scientific advancements have enhanced the understanding of the functional roles played by various components of the holobiont ...
Arts, M.G.I. +21 more
core +3 more sources
Choice of an antihistamine administration route in the treatment of allergic diseases [PDF]
Терапевтический архив, 2016 Allergic diseases (AD) are an interdisciplinary problem in practical health care and characterized by high prevalence, severity, and huge financial costs of their treatment, prevention, and rehabilitation in patients.
L V Luss
doaj
Muscarinic receptor agonists and antagonists [PDF]
, 2001 A comprehensive review of pharmacological and medical aspects of the muscarinic class of acetylcholine agonists and antagonists is presented. The therapeutic benefits of achieving receptor subtype selectivity are outlined and applications in the ...
Broadley, Kenneth John, Kelly, David R.
core +2 more sources
3-Amidoquinuclidine Derivatives: Synthesis and Interaction with Butyrylcholinesterase [PDF]
, 2007 Racemates as well as (R)- and (S)-enantiomers of 3-pivalamidoquinuclidine (PivQ) and 3-acetamidoquinuclidine (AcQ) were prepared. Their quaternary racemic and enantiomerically pure N-benzyl derivatives (BnlPivQ and BnlAcQ) were synthesized as well.
Ines Primožič +2 more
core +3 more sources
The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio +2 more
wiley +2 more sources
Fused and spiro nitrogen heterocycles of quinuclidine and its C-nucleosides [PDF]
, 2011 Quinuclidin-3-one (1) was used as a versatile intermediate for the synthesis of fused and spiro quinuclidine and its C-nucleosides. The reaction of 1 with formalin and secondary amines namely; morpholine, piperidine, and piperazine afforded the ...
El-Magid, Osama Abd +2 more
core +1 more source
The Quest for Palladium-Catalysed Alkyl-Nitrogen Bond Formation [PDF]
, 2016 Our interest in the development of transition-metal catalysis for the realisation of vicinal diamination reactions of alkenes started about a decade ago.
Iglesias, A, Martínez, C, Muñiz, K
core +1 more source
Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance
Chemistry – A European Journal, Volume 32, Issue 19, 22 May 2026.This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini +3 more
wiley +1 more source