RdmA Is a Key Regulator in Autoinduction of DSF Quorum Quenching in Pseudomonas nitroreducens HS-18 [PDF]
mBio, 2023 Diffusible signal factor (DSF) represents a family of widely conserved quorum-sensing (QS) signals which regulate virulence factor production and pathogenicity in numerous Gram-negative bacterial pathogens.
Huishan Wang +5 more
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Quorum quenching by endophytic Bacillus cereus AL1: a lactonase-based anti-virulence strategy against Pseudomonas aeruginosa [PDF]
BMC MicrobiologyBackground Pseudomonas aeruginosa infections are often challenging to treat due to multiple drug resistance, besides the development of biofilms and a plethora of virulence factors regulated by quorum sensing.
Alaa A. Fawzy +3 more
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Quorum Quenching Agents: Resources for Antivirulence Therapy [PDF]
Marine Drugs, 2014 The continuing emergence of antibiotic-resistant pathogens is a concern to human health and highlights the urgent need for the development of alternative therapeutic strategies.
Kaihao Tang, Xiao-Hua Zhang
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Quorum Quenching Approaches against Bacterial-Biofilm-Induced Antibiotic Resistance [PDF]
AntibioticsWith the widespread phenomenon of antibiotic resistance and the diffusion of multiple drug-resistant bacterial strains, enormous efforts are being conducted to identify suitable alternative agents against pathogenic microorganisms.
Patrizia D’Aquila +6 more
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Novel T4ASS effector with quorum quenching activity. [PDF]
ISME J, 2023 Venturi V, Bez C.
europepmc +3 more sources
Exploiting Quorum Sensing Interfering Strategies in Gram-Negative Bacteria for the Enhancement of Environmental Applications [PDF]
, 2016 Quorum sensing (QS) is a widespread intercellular form of communication to coordinate physiological processes and cooperative activities of bacteria at the population level, and it depends on the production, secretion, and detection of small diffusible ...
Chenghua Li, Weiwei Zhang
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Computational and Structural Biotechnology Journal, 2021 Acyl-homoserine lactone (AHL) is the most studied autoinducer in gram-negative bacteria controlling infections of various pathogens. Quenching of AHL signaling by inhibiting AHL synthesis or AHL-receptor binding via small molecular chemicals or ...
Jinxing Liao +8 more
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Majalah Kedokteran Andalas, 2020 Background: Quorum-sensing is communication between bacterial involved in virulence. Bacterial virulence can be inhibited by quorum-quenching mechanism. Endophytic bacteria of pegagan leaf may produce secondary metabolit similar to bioactive compounds in
Nur Al Huda +4 more
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Resistance to Quorum-Quenching Compounds [PDF]
Applied and Environmental Microbiology, 2013 ABSTRACT Bacteria have the remarkable ability to communicate as a group in what has become known as quorum sensing (QS), and this trait has been associated with important bacterial phenotypes, such as virulence and biofilm formation. Bacteria also have an incredible ability to evolve resistance to all known antimicrobials.
Rodolfo, García-Contreras +2 more
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Quorum Sensing Interfering Strategies and Their Implications in the Management of Biofilm-Associated Bacterial Infections [PDF]
Brazilian Archives of Biology and Technology, 2020 The bacterial species employ various types of molecular communication systems recognized as quorum sensing for the synchronization of differential gene expression to regulate virulence traits and biofilm formation. A variety of quorum sensing inhibitors;
Samman Munir +8 more
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