Results 181 to 190 of about 903,028 (272)

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam, Michelle Khai Khun Yap, Rafael Giacomazzi, Sérgio F. Sousa, Hock Siew Tan   +4 more
wiley   +1 more source

Targeting Quorum Sensing to Combat Foodborne Pathogens: A Dual Strategy Against Spoilage and Pathogenesis. [PDF]

Foods
Niu C, Yang J, Kong C, Cai R, Yuan Y, Yue T.   +5 more
europepmc   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

4-Aminobenzoic acid attenuates <i>Ralstonia solanacearum</i> virulence by suppressing quorum sensing system. [PDF]

Virulence
Yao C, Zhang W, Lin Z, Han H, Huang S, Tang L, Sun X, Deng Y, Song S.   +8 more
europepmc   +1 more source

Structural and mutational analysis of Methanosarcina mazei prenylated FMN synthase reveals the basis of its unique prenyl donor substrate specificity

The FEBS Journal, EarlyView.
Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara, Hideaki Unno, Soma Ishimine, Ryuhei Nagata, Tomokazu Ito, Hisashi Hemmi   +5 more
wiley   +1 more source

Spatial distribution and structural discrimination of quorum sensing metabolites in <i>Pseudomonas aeruginosa</i> by MALDI-MSI.

Analyst
Kuik C, van Hoogstraten SWG, Mayrginther L, Arts JJC, Honing M, Cillero-Pastor B.   +5 more
europepmc   +1 more source

Bacterial quorum-sensing systems in cell-cell communication. [PDF]

FEMS Microbiol Rev
Xu KZ, Vinothkanna A, Wang D, Jiang H, Xu Z, Jia AQ.   +5 more
europepmc   +1 more source

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

The FEBS Journal, EarlyView.
A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong, Mateo P. Hoare, Laura J. Grundy, Filomena Gallo, Karin H. Müller, Ewan St. John Smith, Janet R. Kumita   +6 more
wiley   +1 more source

Quorum sensing gene <i>abaI</i> enhancing capsule production and pathogenicity of <i>Acinetobacter baumannii</i>. [PDF]

Front Microbiol
Qiu Z, Zheng Y, Yuan K, Zhao P, Wu G, Zeng Y, Cao H, Zhao X, Hong L, Guo G, Mo F, Wang Y, Peng J.   +12 more
europepmc   +1 more source

Potential of organogel‐based colloidal hydrogels for new cosmetic formulations

International Journal of Cosmetic Science, EarlyView.
Colloidal hydrogels are formed by combining anionic, cationic, or nonionic surfactants with two oils of cosmetic interest: sweet almond oil and phytosqualane. These systems are obtained through hot emulsification followed by cooling, which leads to the aggregation of gel‐like particles.
Andrea Gregorio Gomes, Lea Broche, Bruno Payre, Emile Perez, Celine Picard, Sophie Franceschi   +5 more
wiley   +1 more source