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Quorum sensing plays a necessary role in the production of virulence factors and the formation of biofilm on Pseudomonas aeruginosa. Thus, the development of inhibition of quorum sensing is one of the most promising methods to control bacterial infection
Zhenyu Wei +9 more
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Faced with the global health threat of increasing resistance to antibiotics, researchers are exploring interventions that target bacterial virulence factors.
Osmel Fleitas Martínez +15 more
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Quorum sensing and its inhibition mechanisms [PDF]
The article is a brief literature review. This article provides an overview of the Quorum Sensing system in bacterial communities, highlighting the peculiarities of the system for gram-positive and gramnegative microorganisms. Basic information about the
Prazdnova Evgeniya +7 more
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The main acne-causing bacteria are Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis. Quorum sensing, an important factor for bacterial survival, is closely associated with expression of bacterial virulence factors and biofilm
Liqi LUO +4 more
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Inhibition of bacterial quorum sensing (general concept)
The scientific review outlines current data characterizing the main provisions on the functioning of the mechanism of the sensory quorum in the system of interbacterial communications.
А.Е. Abaturov, Т.А. Kryuchko
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Quorum Sensing Interfering Strategies and Their Implications in the Management of Biofilm-Associated Bacterial Infections [PDF]
The bacterial species employ various types of molecular communication systems recognized as quorum sensing for the synchronization of differential gene expression to regulate virulence traits and biofilm formation. A variety of quorum sensing inhibitors;
Samman Munir +8 more
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Bacteria use a cell-to-cell communication activity termed Quorum sensing to coordinate group behaviors in a cell-density dependent manner. Quorum sensing influences the expression profile of diverse genes, including antibiotic tolerance and virulence ...
Hidetada eHirakawa, Haruyoshi eTomita
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Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
Quorum sensing system plays an active role in the regulation of pathogenicity of many microorganisms. Inhibition of pathogenicity or virulence factors will increase the success of treatment by preventing the development of antibiotic resistance.
Demet Erdönmez +2 more
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In Silico Screening of Quorum Sensing Inhibitor Candidates Obtained by Chemical Similarity Search
Quorum sensing (QS) is a bacterial communication using signal molecules, by which they sense population density of their own species, leading to group behavior such as biofilm formation and virulence.
Sharath Belenahalli Shekarappa +2 more
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Growing evidence suggests that biofilm formation in Pseudomonas aeruginosa (PA) results from quorum sensing, reducing bacterial sensitivity to antibiotics and fostering the development of antibiotic-resistant strains.
Nur Aziz +3 more
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