The Molecular Architecture of Pseudomonas aeruginosa Quorum-Sensing Inhibitors [PDF]
Marine Drugs, 2022 The survival selection pressure caused by antibiotic-mediated bactericidal and bacteriostatic activity is one of the important inducements for bacteria to develop drug resistance.
Qiaoqiang Li +3 more
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Quorum Sensing Inhibitors from Marine Microorganisms and Their Synthetic Derivatives
Marine Drugs, 2019 Quorum sensing inhibitors (QSIs) present a promising alternative or potent adjuvants of conventional antibiotics for the treatment of antibiotic-resistant bacterial strains, since they could disrupt bacterial pathogenicity without imposing selective ...
Jianwei Chen +7 more
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Research Progress on Quorum Sensing and Quorum Sensing Inhibitors of Aeromonas [PDF]
Shipin Kexue, 2023 Bacterial quorum sensing (QS) is a process in which bacteria conduct chemical communication through the production, release, accumulation and induction of signaling molecules called autoinducers (AI).
TU Mingxia, LIU Lei, GAO Liang, ZHANG Ying, GUI Meng, RAO Yu
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Design, synthesis, and biological evaluation of benzoheterocyclic sulfoxide derivatives as quorum sensing inhibitors in Pseudomonas aeruginosa [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Six series of benzoheterocyclic sulfoxide derivatives were designed and synthesised as Pseudomonas aeruginosa (P. aeruginosa) quorum sensing inhibitors in this paper.
Shen Mao +5 more
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Exploration of CviR-mediated quorum sensing inhibitors from Cladosporium spp. against Chromobacterium violaceum through computational studies [PDF]
Scientific Reports, 2023 An opportunistic human pathogenic bacterium, Chromobacterium violaceum resists the potency of most antibiotics by exploiting the quorum sensing system within their community to control virulence factor expression.
Mahadevamurthy Murali +9 more
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Secondary Metabolites of Actinomycetales as Potent Quorum Sensing Inhibitors Targeting Gram-Positive Pathogens: In Vitro and In Silico Study [PDF]
Metabolites, 2022 Anti-virulence agents are non-bacteriostatic and non-bactericidal emerging therapeutic options which hamper the production of virulence factors in pathogenic flora.
Said E. Desouky +9 more
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Fungal Quorum-Sensing Molecules and Inhibitors with Potential Antifungal Activity: A Review
Molecules, 2019 The theory of persisting independent and isolated regarding microorganisms is no longer accepted. To survive and reproduce they have developed several communication platforms within the cells which facilitates them to adapt the surrounding environmental ...
Arshad Mehmood +5 more
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Design of Nanosystems for the Delivery of Quorum Sensing Inhibitors: A Preliminary Study [PDF]
Molecules, 2020 Biofilm production is regulated by the Quorum Sensing system. Nowadays, Quorum Sensing represents an appealing target to design new compounds to increase antibiotics effects and avoid development of antibiotics multiresistance.
Supandeep Singh Hallan +8 more
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Quorum Sensing and Quorum Quenching with a Focus on Cariogenic and Periodontopathic Oral Biofilms
Microorganisms, 2022 Numerous in vitro studies highlight the role of quorum sensing in the pathogenicity and virulence of biofilms. This narrative review discusses general principles in quorum sensing, including Gram-positive and Gram-negative models and the influence of ...
Patricia P. Wright +1 more
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Pharmaceutics, 2022 Chemical molecules are used by microorganisms to communicate with each other. Quorum sensing is the mechanism through which microorganisms regulate their population density and activity with chemical signaling.
Alessandro Polizzi +5 more
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