Results 21 to 30 of about 13,305 (277)
Garlic-Derived Quorum Sensing Inhibitors: A Novel Strategy Against Fungal Resistance. [PDF]
Drug Des Devel TherNa Li,1,2 Junli Zhang,3 Fei Yu,1,2 Fanghang Ye,1,2 Wanying Tan,4 Liyuan Hao,1,2 Shenghao Li,1,2 Jiali Deng,1,2 Xiaoyu Hu2 1Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China ...
Li N +8 more
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Quorum Sensing Inhibitors: An Alternative Strategy to Win the Battle against Multidrug-Resistant (MDR) Bacteria [PDF]
MoleculesHelal F Hetta +2 more
exaly +2 more sources
Pharmaceutics, 2022 Chemical molecules are used by microorganisms to communicate with each other. Quorum sensing is the mechanism through which microorganisms regulate their population density and activity with chemical signaling.
Alessandro Polizzi +5 more
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Effect of Autoinducer-2 Quorum Sensing Inhibitor on Interspecies Quorum Sensing
Frontiers in Microbiology, 2022 Bacterial drug resistance caused by overuse and misuse of antibiotics is common, especially in clinical multispecies infections. It is of great significance to discover novel agents to treat clinical bacterial infections. Studies have demonstrated that autoinducer-2 (AI-2), a signal molecule in quorum sensing (QS), plays an important role in ...
Kai Jiang +16 more
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Breaking down bacterial communication: a review of quorum quenching agents
Future Journal of Pharmaceutical Sciences, 2023 Background Bacterial cells communicate via small extracellular molecules that facilitate gene expression which is dependent on cell density and this mechanism is known as Quorum Sensing (QS).
Tresa Boban, Sahaya Nadar, Savita Tauro
doaj +1 more source
Scientia Pharmaceutica, 2023 In the new antibiotic era, the exponential increase in multiresistant bacterial strains has become the main global health problem. Many researchers have focused their efforts on exploring novel or combined strategies for combating bacterial resistance ...
Petya D. Dimitrova +2 more
doaj +1 more source
Caffeine as a Potential Quorum Sensing Inhibitor [PDF]
Sensors, 2013 Quorum sensing enables bacteria to control the gene expression in response to the cell density. It regulates a variety of bacterial physiological functions such as biofilm formation, bioluminescence, virulence factors and swarming which has been shown contribute to bacterial pathogenesis.
Siti Nur Maisarah Norizan +2 more
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Evolution of Resistance to Quorum-Sensing Inhibitors [PDF]
Microbial Ecology, 2013 The major cause of mortality and morbidity in human beings is bacterial infection. Bacteria have developed resistance to most of the antibiotics primarily due to large-scale and "indiscriminate" usage. The need is to develop novel mechanisms to treat bacterial infections. The expression of pathogenicity during bacterial infections is mediated by a cell
Vipin C, Kalia +2 more
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Identification of novel phenylalanine derivatives bearing a hydroxamic acid moiety as potent quorum sensing inhibitors. [PDF]
RSC Med ChemPhenylalanine derivatives are a well-known small moiety responsible for controlling the virulence factors of several bacteria. Herein, for the first time, we report novel structures of phenylalanine derivatives bearing a hydroxamic acid moiety which were
Tung TT +6 more
europepmc +2 more sources
Quorum sensing inhibitors: a bargain of effects [PDF]
Microbiology, 2006 Many opportunistic pathogenic bacteria rely on quorum sensing (QS) circuits as central regulators of virulence expression. In Pseudomonas aeruginosa, QS-regulated gene expression contributes to the formation and maintenance of biofilms and their tolerance to conventional antimicrobials and the host innate immune system.
Thomas B, Rasmussen, Michael, Givskov
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