Biofilm Formation, Antimicrobial Resistance and Control of Vibrio Based on Quorum Sensing: A Review
: Vibrio, Gram-negative pathogenic bacterium, are commonly found in aquatic environments. Not only it can cause food poisoning and wound infection in humans, but also easily lead to spoilage in seafood. Biofilm formation regulated by quorum sensing is an
Xueqing LIU +3 more
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Evolution of Resistance to Quorum-Sensing Inhibitors [PDF]
The major cause of mortality and morbidity in human beings is bacterial infection. Bacteria have developed resistance to most of the antibiotics primarily due to large-scale and "indiscriminate" usage. The need is to develop novel mechanisms to treat bacterial infections. The expression of pathogenicity during bacterial infections is mediated by a cell
Vipin C, Kalia +2 more
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Bacterial resistance represents one of the emerging obstacles in plants, animals, and humans that impairs treatment with antibacterial agents. Targeting of the bacterial quorum sensing system is one of the strategies to overcome this problem.
Islam Mostafa +6 more
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Quorum sensing inhibitors: a bargain of effects [PDF]
Many opportunistic pathogenic bacteria rely on quorum sensing (QS) circuits as central regulators of virulence expression. In Pseudomonas aeruginosa, QS-regulated gene expression contributes to the formation and maintenance of biofilms and their tolerance to conventional antimicrobials and the host innate immune system.
Thomas B, Rasmussen, Michael, Givskov
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Research progress on quorum sensing in the caries-causing effects of Streptococcus mutans and Candida albicans [PDF]
Dental caries is a major disease that seriously endangers human oral health. Dental plaque biofilm composed of many microorganisms is the primary factor of dental caries. Inhibiting biofilm formation has become the focus of research on the prevention and
LIAO Zhenzhen, LI Wenxiu, LIANG Yan
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Quorum Sensing of Periodontal Pathogens
The term ‘quorum sensing’ describes intercellular bacterial communication which regulates bacterial gene expression according to population cell density. Bacteria produce and secrete small molecules, named autoinducers, into the intercellular space.
Darije Plančak +2 more
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Attenuation of quorum sensing system and virulence in Vibrio cholerae by phytomolecules
The Vibrio cholerae, a gram-negative bacterium, is the causative agent of cholera. Quorum sensing is a cell-to-cell communication that leads to gene expression, accumulation of signaling molecules, biofilm formation, and production of virulence factors ...
Subhasree Saha +4 more
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The role of cell to cell interactions and quorum sensing in formation of biofilms in drinking water bacteria [PDF]
Microorganisms such as bacteria, fungi, viruses and protozoa in drinking water distribution systems readily colonize the pipe surfaces and form biofilms.
Ramalingam, Bharathi
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Synergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P.aeruginosa Quorum Sensing [PDF]
ABSTRACT The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence genes and formation of drug-resistance biofilms.
Fong, July +9 more
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Food as a Source for Quorum Sensing Inhibitors: Iberin from Horseradish Revealed as a Quorum Sensing Inhibitor of Pseudomonas aeruginosa [PDF]
ABSTRACT Foods with health-promoting effects beyond nutritional values have been gaining increasing research focus in recent years, although not much has been published on this subject in relation to bacterial infections. With respect to treatment, a novel antimicrobial strategy, which is expected to transcend problems with ...
Jakobsen, Tim Holm +10 more
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