Results 21 to 30 of about 958,198 (238)

Emerging evidence-based innovative approaches to control catheter-associated urinary tract infection: a review

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Healthcare settings have dramatically advanced the latest medical devices, such as urinary catheters (UC) for infection, prevention, and control (IPC). The continuous or intermittent flow of a warm and conducive (urine) medium in the medical device, the ...
Shobana Rajaramon   +3 more
doaj   +1 more source

Polymer based dual drug delivery system for targeted treatment of fluoroquinolone resistant Staphylococcus aureus mediated infections

open access: yesScientific Reports, 2023
The present study attempts to treat S. aureus-induced soft skin infections using a combinatorial therapy with an antibiotic, Ciprofloxacin (CIP), and an efflux pump inhibitor 5-Nitro-2-(3-phenylpropoxy) pyridine (5-NPPP) through a smart hydrogel delivery
Gopalakrishnan Thamilselvan   +6 more
doaj   +1 more source

Quorum Sensing and Quorum Quenching with a Focus on Cariogenic and Periodontopathic Oral Biofilms

open access: yesMicroorganisms, 2022
Numerous in vitro studies highlight the role of quorum sensing in the pathogenicity and virulence of biofilms. This narrative review discusses general principles in quorum sensing, including Gram-positive and Gram-negative models and the influence of ...
Patricia P. Wright   +1 more
doaj   +1 more source

Development of a smart pH-responsive nano-polymer drug, 2-methoxy-4-vinylphenol conjugate against the intestinal pathogen, Vibrio cholerae

open access: yesScientific Reports, 2023
Vibrio cholerae causes cholera, an acute diarrhoeal disease. The virulence in V. cholerae is regulated by the quorum-sensing mechanism and response regulator LuxO positively regulates the expression of virulence determinants adhesion, biofilm formation ...
Hema Bhagavathi Sarveswari   +3 more
doaj   +1 more source

Exploration of Anti-infectives From Mangrove-Derived Micromonospora sp. RMA46 to Combat Vibrio cholerae Pathogenesis

open access: yesFrontiers in Microbiology, 2020
Vibrio cholerae, the etiological agent of cholera, employs quorum sensing (QS) pathways to control the expression of virulence factors, including the production of cholera toxin and biofilm formation. Acquired antibiotic resistance in V.
Hema Bhagavathi Sarveswari   +4 more
doaj   +1 more source

Reciprocal Cooperation of Type A Procyanidin and Nitrofurantoin Against Multi-Drug Resistant (MDR) UPEC: A pH-Dependent Study

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Uropathogenic Escherichia coli (UPEC) accounts for the majority of complicated and uncomplicated urinary tract infections. The use of phytomolecules in the treatment of UTI is fast gaining attention.
Sahana Vasudevan   +4 more
doaj   +1 more source

Staphylococcus aureus Quorum Regulator SarA Targeted Compound, 2-[(Methylamino)methyl]phenol Inhibits Biofilm and Down-Regulates Virulence Genes

open access: yesFrontiers in Microbiology, 2017
Staphylococcus aureus is a widely acknowledged Gram-positive pathogen for forming biofilm and virulence gene expressions by quorum sensing (QS), a cell to cell communication process. The quorum regulator SarA of S.
P. Balamurugan   +5 more
doaj   +1 more source

Breaking down bacterial communication: a review of quorum quenching agents

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background Bacterial cells communicate via small extracellular molecules that facilitate gene expression which is dependent on cell density and this mechanism is known as Quorum Sensing (QS).
Tresa Boban, Sahaya Nadar, Savita Tauro
doaj   +1 more source

Structural studies of Vibrio cholerae quorum sensing proteins [PDF]

open access: yes, 2012
The spread of cholera is always associated with contaminated food or water and this is the reason this disease has been endemic in developing countries for centuries due to their lack of proper sanitation facilities and poor or no infrastructure for ...
Jahan, Nasrin
core   +2 more sources

Cheater suppression and stochastic clearance through quorum sensing.

open access: yesPLoS Computational Biology, 2022
The evolutionary consequences of quorum sensing in regulating bacterial cooperation are not fully understood. In this study, we reveal unexpected effects of regulating public good production through quorum sensing on bacterial population dynamics ...
Alexander S Moffett   +3 more
doaj   +1 more source

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