Results 71 to 80 of about 103,320 (332)

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Mitigating candidiasis with acarbose by targeting Candida albicans α-glucosidase: in-silico, in-vitro and transcriptomic approaches

Scientific Reports
Biofilm-associated candidiasis poses a significant challenge in clinical settings due to the limited effectiveness of existing antifungal treatments. The challenges include increased pathogen virulence, multi-drug resistance, and inadequate penetration ...
Helma David, Sahana Vasudevan, Adline Princy Solomon   +2 more
doaj   +1 more source

Attenuation of quorum sensing system and virulence in Vibrio cholerae by phytomolecules

Frontiers in Microbiology, 2023
The Vibrio cholerae, a gram-negative bacterium, is the causative agent of cholera. Quorum sensing is a cell-to-cell communication that leads to gene expression, accumulation of signaling molecules, biofilm formation, and production of virulence factors ...
Subhasree Saha, Subhasree Saha, Shifu Aggarwal, Durg Vijai Singh, Durg Vijai Singh   +4 more
doaj   +1 more source

3D Printing of Functional Mesoporous Silica Monoliths with Embedded Metal and MOF Components

Advanced Functional Materials, EarlyView.
This article presents the development of silica nanocage‐based nano‐inks tailored for digital light processing 3D printing, enabling automated additive manufacturing of mesoporous monoliths. Novel strategies for incorporating metal sites and inducing in situ growth of metal‐organic frameworks are introduced.
Thomas Gaillard, Arianna Bertero, Christine Joly‐Duhamel, Christine Biolley, Bartolomeo Coppola, Nicolas Brun, Anne Galarneau, Tangi Aubert   +7 more
wiley   +1 more source

Spatial Dispersal of Bacterial Colonies Induces a Dynamical Transition From Local to Global Quorum Sensing

, 2016
Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains.
Boedicker, James Q., Yusufaly, Tahir I.
core   +1 more source

Microfluidic study of the chemotactic response of Escherichia coli to amino acids, signaling molecules and secondary metabolites [PDF]

, 2015
Quorum sensing and chemotaxis both affect bacterial behavior on the population level. Chemotaxis shapes the spatial distribution of cells, while quorum sensing realizes a cell-density dependent gene regulation.
Galajda, Péter, Gombai, É., Hodula, O., Kerényi, Ádám, Nagy, Krisztina, Ormos, Pál, Sipos, Orsolya, Valkai, Sándor   +7 more
core   +1 more source

Quorum Sensing by Monocyte-Derived Populations [PDF]

Frontiers in Immunology, 2019
Quorum sensing is a type of cellular communication that was first described in bacteria, consisting of gene expression regulation in response to changes in cell-population density. Bacteria synthesize and secrete diffusive molecules called autoinducers, which concentration varies accordingly with cell density and can be detected by the producing cells ...
Jérémy Postat, Jérémy Postat, Philippe Bousso   +2 more
openaire   +5 more sources

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim, Hwi Won Seo, Kyuri Lee, Dongeun Yong, Yoon Kyung Park, Yujin Lee, Solip Lee, Do‐Wan Kim, Dajeong Kim, Choong‐Min Ryu   +9 more
wiley   +1 more source

Research progress on quorum sensing in the caries-causing effects of Streptococcus mutans and Candida albicans [PDF]

口腔疾病防治
Dental caries is a major disease that seriously endangers human oral health. Dental plaque biofilm composed of many microorganisms is the primary factor of dental caries. Inhibiting biofilm formation has become the focus of research on the prevention and
LIAO Zhenzhen, LI Wenxiu, LIANG Yan
doaj   +1 more source

Characterization of phenotype variations of luminescent and non-luminescent variants of Vibrio harveyi wild type and quorum sensing mutants

, 2016
Vibrio harveyi, a luminescent Gram-negative motile marine bacterium, is an important pathogen responsible for causing severe diseases in shrimp, finfish and molluscs leading to severe economic losses.
Baruah, Sri Kartik, Bossier, Peter, Nguyen Thi Xuan, Hong, Vanrompay, Daisy   +3 more
core   +1 more source