Results 81 to 90 of about 958,198 (238)

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Can the natural diversity of quorum sensing advance synthetic biology?

Frontiers in Bioengineering and Biotechnology, 2015
Quorum-sensing networks enable bacteria to sense and respond to chemical signals produced by neighboring bacteria. They are widespread: over one hundred morphologically and genetically distinct species of eubacteria are known to use quorum sensing to ...
Rene Michele Davis, Rene Michele Davis, Ryan Yue Muller, Ryan Yue Muller, Karmella Ann Haynes   +4 more
doaj   +1 more source

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Research progress on the mechanisms by which plant-originated quorum sensing inhibitors inhibit pathogenic bacteria of acne

Pifu-xingbing zhenliaoxue zazhi
The main acne-causing bacteria are Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis. Quorum sensing, an important factor for bacterial survival, is closely associated with expression of bacterial virulence factors and biofilm
Liqi LUO, Liuqi ZHENG, Jingyi LU, Hai ZHANG, Li BAI   +4 more
doaj   +1 more source

Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

Advanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw, Niyamat M. A. Chimthanawala, Shouvik Manna, Sadhana Sathaye, Samir K. Maji   +4 more
wiley   +1 more source

Interference of bacterial cell-to-cell communication: A new concept of antimicrobial chemotherapy breaks antibiotic

Frontiers in Microbiology, 2013
Bacteria use a cell-to-cell communication activity termed Quorum sensing to coordinate group behaviors in a cell-density dependent manner. Quorum sensing influences the expression profile of diverse genes, including antibiotic tolerance and virulence ...
Hidetada eHirakawa, Haruyoshi eTomita
doaj   +1 more source

Living Electronics: Microbial Metabolism as Batteries, Resistors, and Capacitors

Advanced Electronic Materials, EarlyView.
Three microorganisms are assigned the three elementary roles of a circuit on one sheet of paper. Dormant Bacillus subtilis spores germinate to switch the power source on; a photosynthetic Synechocystis biofilm sets resistance by the color and intensity of light; and a respiring Shewanella oneidensis biofilm stores charge. Together they form a printable
Botian Wang, Ruohan Zhang, Seokheun Choi
wiley   +1 more source

Quorum sensing and its inhibition mechanisms [PDF]

BIO Web of Conferences
The article is a brief literature review. This article provides an overview of the Quorum Sensing system in bacterial communities, highlighting the peculiarities of the system for gram-positive and gramnegative microorganisms. Basic information about the
Prazdnova Evgeniya, Bren Anzhelica, Golovko Lilia, Teperin Alexander, Xu Delin, Zhao Xinqing, Chikindas Michael, Rudoy Dmitry   +7 more
doaj   +1 more source

Nanocrystalline LCO/LLZO Composite Cathode Films for Solid State Batteries

Advanced Energy Materials, EarlyView.
A single precursor solution is solution‐deposited and calcined at only 750°C to yield a dense, nanograined LiCoO2/LLZO composite cathode, in which both phases crystallize independently with minimal interdiffusion. Assembled into all‐solid‐state Li‐metal batteries, the composite delivers 111.7 mAh g−1 initial discharge capacity and retains 93% after 100
Lucie Quincke, Steffen Weinmann, Jesse J. Hinricher, Matteo Galasso, Chiara Althammer, Fran Kurnia, Kun Joong Kim, Wolff‐Ragnar Kiebach, Jennifer L. M. Rupp   +8 more
wiley   +1 more source

The atypical quorum sensing system of classical Brucella species

Journal of Bacteriology
Brucella species are notorious pathogens of animals and humans and cause significant morbidity and economic losses globally. These hardy bacteria have evolved to survive and replicate in host cells, particularly macrophages, and have developed a ...
Mitchell T. Caudill, Clayton C. Caswell
doaj   +1 more source