Results 151 to 160 of about 14,058 (169)
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ChemMedChem, 2018
AbstractWe report a 100‐fold increase in binding affinity of the Tat(48–57) peptide to HIV‐1 transcriptional activator‐responsive element (TAR) RNA by replacing Arg52, an essential and critical residue for Tat's specific binding, with (2S,4S)‐4‐guanidinoproline.
Govind S. Bhosle +5 more
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AbstractWe report a 100‐fold increase in binding affinity of the Tat(48–57) peptide to HIV‐1 transcriptional activator‐responsive element (TAR) RNA by replacing Arg52, an essential and critical residue for Tat's specific binding, with (2S,4S)‐4‐guanidinoproline.
Govind S. Bhosle +5 more
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Biochemistry, 2006
Mutating arginine 52 to glutamine (R52Q) in photoactive yellow protein (PYP) increases the pK(a) of the chromophore by 1 pH unit. The structure of the R52Q PYP mutant was determined by X-ray crystallography and was compared to the structure of wild-type PYP to assess the role of R52 in pK(a) regulation.
Nobutaka, Shimizu +4 more
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Mutating arginine 52 to glutamine (R52Q) in photoactive yellow protein (PYP) increases the pK(a) of the chromophore by 1 pH unit. The structure of the R52Q PYP mutant was determined by X-ray crystallography and was compared to the structure of wild-type PYP to assess the role of R52 in pK(a) regulation.
Nobutaka, Shimizu +4 more
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Molecular Pharmacology, 1997
The hepatic UDP-glucuronosyltransferase UGT1*6 is actively involved in the glucuronidation of short and planar phenols in humans. Based on the irreversible inhibition of the enzyme on chemical modification by 2,3-butanedione and diethyl pyrocarbonate, the roles of His54 and Arg52 were investigated by oligonucleotide site-directed mutagenesis.
C, Senay +8 more
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The hepatic UDP-glucuronosyltransferase UGT1*6 is actively involved in the glucuronidation of short and planar phenols in humans. Based on the irreversible inhibition of the enzyme on chemical modification by 2,3-butanedione and diethyl pyrocarbonate, the roles of His54 and Arg52 were investigated by oligonucleotide site-directed mutagenesis.
C, Senay +8 more
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The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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Diplomová práce se zabývá napojením ulice Vídeňské na budoucí obytné zástavby ležící mezi Přízřenicemi a Modřicemi. Tato práce je zpracována na úrovni technické studie. Předmětem této práce je návrh mimoúrovňové křižovatky na ulici Vídeňská a Moravanská.
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R52: Rôle des cadhérines et des GTPases Rho dans le caractère invasif des rhabdomyosarcomes
Bulletin du Cancer, 2010S. Thuault +3 more
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Zavěšený most přes rychlostní komunikaci R52
Práce se zabývá statickou, dynamickou analýzou zavěšené mostní konstrukce a návrhem nosné konstrukce podle mezních stavů. Součástí práce je statický výpočet, výkresová dokumentace a vizualizace.openaire +1 more source

