Results 101 to 110 of about 24,778 (199)

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]

, 2012
Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve
A. Lucas, A. M. English, A. Sette, A. Wriston, B. J. Grant, B. Peters, C. A. F. de Oliveira, C. Oseroff, Cahalan, Chessman, Chung, D. A. Ostrov, D. F. Hunt, Day, E. Phillips, Faletto, Friesner, H. M. Grey, H. Mei, Harndahl, J. Jakoncic, J. Shabanowitz, J. Sidney, Ko, L. Shi, L. Yang, Lavergne, M. Harndahl, Mallal, Martin, Melroy, Phillips, Pichler, Rudolph, S. Buus, S. Lu, S. Mallal, S. Southwood, Shastri, Shimizu, Sidney, Sidney, Tenzer, Udeshi, Y. A. Pompeu, Yang, Yang, Yewdell   +47 more
core   +4 more sources

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus [PDF]

, 1994
We have examined the modifications occurring during the transformation of phagosomes into phagolysosomes in J-774 macrophages. The use of low density latex beads as markers of phagosomes (latex bead compartments, LBC) allowed the isolation of these ...
Desjardins, M., Griffiths, G., Huber, L. A., Parton, R. G.   +3 more
core   +4 more sources

The Role of the Early Secretory Pathway in Foot-and-Mouth Disease Virus Replication

, 2011
Foot-and-Mouth Disease Virus (FMDV) induces rearrangements of host-cell membranes to generate vesicles that are believed to provide platforms for formation of the viral replication complex. The cellular origin of these vesicles and the properties that
Midgley, Rebecca Julie, Midgley, Rebecca Julie   +1 more
core   +1 more source

Exosome Biogenesis, Regulation, and Function in Viral Infection [PDF]

, 2015
Exosomes are extracellular vesicles released upon fusion of multivesicular bodies(MVBs) with the cellular plasma membrane. They originate as intraluminal vesicles (ILVs) duringthe process of MVB formation.
Alenquer, Marta, Amorim, Maria
core   +2 more sources

Mammalian evolution and human mutation burden in Rab GTPases. [PDF]

Biochem Biophys Rep
Sidor U, Hughes GM, Simpson JC.
europepmc   +1 more source

Insight into the Interactions Between GhXI-K and Rab GTPases in Cotton Fiber. [PDF]

Plants (Basel)
Li X, Hao B, Li J, Jia Y.
europepmc   +1 more source

Rab5 nucleotide binding promotes oxidative metabolism to fuel hepatocellular carcinoma cell proliferation. [PDF]

J Biol Chem
Otakhor KO, Zaidi MAA, Oberley-Deegan RE, Ponnusamy MP, Fisher KW, Schott MB.   +5 more
europepmc   +1 more source

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking. [PDF]

J Cell Biol
van Vliet AR, Gillingham AK, Morgan TE, Ohashi Y, Smith TS, Abid Ali F, Munro S.   +6 more
europepmc   +1 more source

Targeting ICMT: A promising strategy in cancer treatment (Review). [PDF]

Oncol Lett
Hu J, Xiao Y, Tang J.
europepmc   +1 more source

Vesicular transport in the autophagic route: RAB GTPases as pivotal regulators of autophagy. [PDF]

Biochem J
Abba R, Colombo MI.
europepmc   +1 more source