Results 111 to 120 of about 45,175 (206)

PACAP induces FSHβ gene expression via EPAC. [PDF]

, 2019
Gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), are heterodimers of a common α subunit and unique β subunits. Regulation of their levels, primarily by GnRH, is critical for reproductive function.
Coss, Djurdjica, Yeh, Debra M
core  

Mechanistic and Functional Studies of Rab7 Phosphorylation [PDF]

, 2016
Rab7调控着从内体到溶酶体以及从内体到高尔基体的囊泡运输过程；也参与了自噬、吞噬过程；同时还调节着溶酶体及其相关细胞器的生成过程。Rab7的功能受到各种相互作用因子的调控；Rab7的功能异常会导致包括神经退行性疾病和肿瘤在内的多种疾病。前期实验发现Rab7与Src在早期内体和晚期内体共定位，另有报道v-Src可激活Rab7，但是Src对Rab7的调节机制尚不清楚。 本研究发现Src、Blk等酪氨酸激酶可磷酸化修饰Rab7，其磷酸化位点为第183位酪氨酸残基 ...
林晓思
core  

Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins.

Biochemical Journal, 1993
Stewart A. Metz, M. Rabaglia, Jeffry B. Stock, Anjaneyulu Kowluru   +3 more
semanticscholar   +1 more source

Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.

Journal of Clinical Investigation, 1996
A. Kowluru, S. Seavey, Guodong Li, Robert L. Sorenson, A. Weinhaus, Rafael Nesher, M. Rabaglia, Jacob Vadakekalam, Stewart A. Metz   +8 more
semanticscholar   +1 more source

Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome

Nature Genetics, 2004
Yanli Fan, M. Esmail, S. J. Ansley, O. Blacque, Keith A. Boroevich, A. Ross, S. Moore, José L. Badano, H. May-Simera, Deanna S Compton, Jane S Green, R. Lewis, M. Haelst, P. Parfrey, D. Baillie, P. Beales, N. Katsanis, W. Davidson, M. Leroux   +18 more
semanticscholar   +1 more source

Identification of new protein species among 33 different small GTP-binding proteins encoded by cDNAs from Lotus japonicus, and expression of corresponding mRNAs in developing root nodules.

The Plant Journal, 1997
Søren Borg, Birgitte Brandstrup, T. J. Jensen, Carsten Poulsen   +3 more
semanticscholar   +1 more source

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking. [PDF]

J Cell Biol
van Vliet AR, Gillingham AK, Morgan TE, Ohashi Y, Smith TS, Abid Ali F, Munro S.   +6 more
europepmc   +1 more source

Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag.

Proceedings of the National Academy of Sciences of the United States of America, 1993
Y. T. Chen, C. Holcomb, H. Moore
semanticscholar   +1 more source

Vesicular transport in the autophagic route: RAB GTPases as pivotal regulators of autophagy. [PDF]

Biochem J
Abba R, Colombo MI.
europepmc   +1 more source

Selectivity profiles and substrate recognition of Rab-phosphorylating kinases. [PDF]

Biochem J
Chatterjee D, Dederer V, Nguyen LV, Wendel M, Abdul Azeez KR, Mahesula S, Stengel F, Reck-Peterson S, Mathea S.   +8 more
europepmc   +1 more source