Biophysical Studies of Rab GTPase Membrane Binding
, 2011 Rab proteins are the largest subfamily of the Ras superfamily of small GTPases, with more than 60 known members, that are involved in a multitude of different processes regulating membrane traffic.
Kirsten, Marie Lis, Kirsten, Marie Lis
core +1 more source
Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans [PDF]
, 2006 Rab small GTPases are involved in the transport of vesicles between different membranous organelles. RAB-3 is an exocytic Rab that plays a modulatory role in synaptic transmission.
Fukuda, Mitsunori +8 more
core +3 more sources
The Interaction Properties of the Human Rab GTPase Family – A Comparative Analysis Reveals Determinants of Molecular Binding Selectivity [PDF]
, 2012 Rab GTPases constitute the largest subfamily of the Ras protein superfamily. Rab proteins regulate organelle biogenesis and transport, and display distinct binding preferences for effector and activator proteins, many of which have not been elucidated ...
A Delprato +63 more
core +4 more sources
Protein Inference and Protein Quantification: Two Sides of the Same Coin [PDF]
arXiv, 2012 Motivation: In mass spectrometry-based shotgun proteomics, protein quantification and protein identification are two major computational problems. To quantify the protein abundance, a list of proteins must be firstly inferred from the sample. Then the relative or absolute protein abundance is estimated with quantification methods, such as spectral ...
arxiv
Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks? [PDF]
arXiv, 2006 In protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein structure. In this paper we investigate the role of protein disorder in the network topology.
arxiv
Refining the Protein-Protein Interactome using Gene Expression Data [PDF]
arXiv, 2010 Proteins interact with other proteins within biological pathways, forming connected subgraphs in the protein-protein interactome (PPI). Proteins are often involved in multiple biological pathways which complicates interpretation of interactions between proteins.
arxiv
Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2 [PDF]
, 2020 Alessi, Dario R. +5 more
core +2 more sources
Protein token: a dynamic unit in protein interactions [PDF]
arXiv, 2018 In this study, we introduced a new unit, named "protein token", as a dynamic protein structural unit for protein-protein interactions. Unlike the conventional structural units, protein token is not based on the sequential or spatial arrangement of residues, but comprises remote residues involved in cooperative conformational changes during protein ...
arxiv
Dinuclear concept - cluster model of fusion [PDF]
arXiv, 1999 The synthesis of superheavy elements is analysed within the dinuclear system concept of compound nucleus formation. The perspectives for using radioactive beams in complete fusion reactions are discussed.
arxiv
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins [PDF]
, 1993 Rab proteins comprise a family of small GTPases that serve a regulatory role in membrane traffic. These proteins are in part cytosolic and in part associated with the membranes of specific exocytic and endocytic organelles.
Alexandrov, Kirill +7 more
core