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Methods for Controlling Small GTPase Activity. [PDF]
Faulkner B, He Y, Sitrin D, Stains CI.
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Axonopathy: mechanisms and potential therapeutic targets for neurodegenerative diseases. [PDF]
Shen R, Sung K, Ding J, Wu C.
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A rab-related GTP-binding protein in Schistosoma mansoni
Molecular and Biochemical Parasitology, 1996Schistosomiasis is a parasitic disease initiated by the deposition of eggs in host tissues by the blood fluke Schistosoma. A gene encoding a low-molecular weight GTP-binding protein (LMWGP) was cloned from Schistosoma mansoni using a polymerase chain reaction (PCR)-based strategy.
I K, Loeffler, J L, Bennett
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Evolution of the rab family of small GTP-binding proteins
Journal of Molecular Biology, 2001Rab proteins are small GTP-binding proteins that form the largest family within the Ras superfamily. Rab proteins regulate vesicular trafficking pathways, behaving as membrane-associated molecular switches. Here, we have identified the complete Rab families in the Caenorhabditis elegans (29 members), Drosophila melanogaster (29), Homo sapiens (60) and ...
J B, Pereira-Leal, M C, Seabra
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An immunologist's look at the Rho and Rab GTP-binding proteins
Immunology Today, 1993The ras superfamily of small GTP-binding proteins contains three major branches: the Ras, Rho and Rab protein subfamilies. Recent advances in the field of ras-related small GTP-binding proteins suggest that it may be worthwhile to look at this superfamily from the standpoint of immunology.
P, Chavrier, J P, Gorvel, J, Bertoglio
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Expression of rab GTP-binding proteins during oligodendrocyte differentiation in culture
Journal of Neuroscience Research, 2000Oligodendrocytes (OLs) synthesize and transport vast amounts of proteins and lipids from the cell body to the morphologically and biochemically distinct domains of the myelin membrane. From our prediction that regulators of vesicular transport should be up-regulated at the time of myelin production, we hypothesized that the up-regulated and ...
B P, Bouverat +4 more
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Cloning and Tissue Expression of the Rat RAB 3C GTP-Binding Protein
Biochemical and Biophysical Research Communications, 1996A cDNA clone which encodes the low molecular weight GTP-binding protein rab 3C was isolated from a rat PC12 pheochromocytoma library. The 1.0 kb clone contains the entire coding region (681 bp), as well as 5' (89 bp) and 3' (230 bp) untranslated sequences.
M, Viggeswarapu, G M, Wildey
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Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2
Nature, 1991Entry of a cell into mitosis induces a series of structural and functional changes including arrest of intracellular transport. Knowledge of how the mitotic cycle is driven progressed substantially with the identification of the p34cdc2 protein kinase as a subunit of maturation-promoting factor, the universal regulating component of the mitotic cycle ...
E, Bailly +5 more
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Small GTP binding proteins: Rab GTPases from the brain of Bombyx mori
Archives of Insect Biochemistry and Physiology, 2003AbstractFrom a mRNA of the brain of Bombyx mori, we isolated 8 cDNA clones (BRabs), each of which encodes a different member of Rabāprotein family. Four of them have more than 80% amino acid identity to the corresponding members of Drosophila Rab proteins. The other 4 proteins show low sequence similarity to any of the known Rab proteins.
Tomohide, Uno, Susumu, Hiragaki
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