Results 151 to 160 of about 25,142 (177)
A rab-related GTP-binding protein in Schistosoma mansoni
Molecular and Biochemical Parasitology, 1996 Schistosomiasis is a parasitic disease initiated by the deposition of eggs in host tissues by the blood fluke Schistosoma. A gene encoding a low-molecular weight GTP-binding protein (LMWGP) was cloned from Schistosoma mansoni using a polymerase chain reaction (PCR)-based strategy.
Loeffler Ik, Bennett Jl
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An immunologist's look at the Rho and Rab GTP-binding proteins
Immunology Today, 1993 The ras superfamily of small GTP-binding proteins contains three major branches: the Ras, Rho and Rab protein subfamilies. Recent advances in the field of ras-related small GTP-binding proteins suggest that it may be worthwhile to look at this superfamily from the standpoint of immunology.
Philippe Chavrier +2 more
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The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach
Gene, 1992 Partial sequences corresponding to eleven novel Rab proteins and one new Rho protein have been isolated using a PCR-based cloning approach. These results confirm that the overall diversity of the Rab and Rho protein subfamilies account for more than thirty different members in mammalian cells.
Philippe Chavrier +2 more
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Evolution of the rab family of small GTP-binding proteins
Journal of Molecular Biology, 2001 Rab proteins are small GTP-binding proteins that form the largest family within the Ras superfamily. Rab proteins regulate vesicular trafficking pathways, behaving as membrane-associated molecular switches. Here, we have identified the complete Rab families in the Caenorhabditis elegans (29 members), Drosophila melanogaster (29), Homo sapiens (60) and ...
José B. Pereira‐Leal +1 more
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Expression of rab GTP-binding proteins during oligodendrocyte differentiation in culture
Journal of Neuroscience Research, 2000 Oligodendrocytes (OLs) synthesize and transport vast amounts of proteins and lipids from the cell body to the morphologically and biochemically distinct domains of the myelin membrane. From our prediction that regulators of vesicular transport should be up-regulated at the time of myelin production, we hypothesized that the up-regulated and ...
B.P. Bouverat +4 more
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Journal of Bioinformatics and Computational Biology, 2018 Deep learning has been increasingly and widely used to solve numerous problems in various fields with state-of-the-art performance. It can also be applied in bioinformatics to reduce the requirement for feature extraction and reach high performance. This study attempts to use deep learning to predict GTP binding sites in Rab proteins, which is one of ...
Nguyen Quoc Khanh Le +2 more
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Gene cloning and characterization of a GTP-binding Rab protein from mouse pituitary AtT-20 cells
Gene, 1993 The Rab proteins constitute a family of Ras-like, low-molecular-weight GTP-binding proteins that are involved in vesicular transport in mammalian cells. Several members of this family have been localized to specific cellular compartments, indicating that they may control vesicular transfer between discrete portions of the endomembrane systems.
Helen Yu +2 more
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Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily
Journal of Cell Science, 1993 ABSTRACT Small GTPases of the rab subfamily are involved in reg-ulation of intracellular membrane transport events. We recently used a PCR approach to isolate short cDNA fragments of a number of novel rab sequences. These PCR fragments have now been used with cDNA library screening and PCR-based techniques to clone the cDNAs encoding ...
Vesa M. Olkkonen +5 more
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