Results 11 to 20 of about 55,282 (252)

This Is the End: Regulation of Rab7 Nucleotide Binding in Endolysosomal Trafficking and Autophagy [PDF]

Frontiers in Cell and Developmental Biology, 2018
Rab7 – or in yeast, Ypt7p – governs membrane trafficking in the late endocytic and autophagic pathways. Rab7 also regulates mitochondrion-lysosome contacts, the sites of mitochondrial fission.
Christopher Stroupe
doaj   +3 more sources

GDP/GTP exchange reaction‐stimulating activity of Rabphilin‐3A for Rab3A small GTP‐binding protein [PDF]

FEBS Letters, 1994
Rabphilin‐3A is a putative target protein for Rab3A, a small GTP‐binding protein particularly implicated in neurotransmitter release. Rabphilin‐3A interacts more preferentially with GTP‐Rab3A than with GDP‐Rab3A. Moreover, Rabphilin‐3A shows a weak activity to stimulate the GTPase activity of Rab3A and a strong activity to inhibit the Rab3A GTPase ...
Yasuyuki Fujita, Takuya Sasaki, Keishi Araki, Kazuo Takahashi, Katsunori Imazumi, Masaki Kato, Yoshiharu Matsuura, Y Takai   +7 more
openalex   +4 more sources

Rabphilin-3A, a Putative Target Protein for smg p25A/rab3A p25 Small GTP-Binding Protein Related to Synaptotagmin [PDF]

Molecular and Cellular Biology, 1993
In a previous study (H. Shirataki, K. Kaibuchi, T. Yamaguchi, K. Wada, H. Horiuchi, and Y. Takai, J. Biol. Chem. 267:10946-10949, 1992), we highly purified from bovine brain crude membranes the putative target protein for smg p25A/rab3A p25, a ras p21-related small GTP-binding protein implicated in neurotransmitter release.
Hiromichi Shirataki, Kozo Kaibuchi, Tsuyoshi Sakoda, Shosei Kishida, Tsutomu Yamaguchi, Ken Wada, Mutsuo Miyazaki, Yoshimi Takai   +7 more
openalex   +5 more sources

Molecular Characterization of a Rab-related Small GTP Binding Protein cDNA from Rice (Oryza sativa L. IR-36)

Molecules and Cells, 1997
To study physiological roles of plant small GTP binding proteins, we isolated a cDNA clone (ORrab2) encoding the rab-related small GTP binding protein from rice (Oryza sativa L. IR-36) by using human cDNA rab2 as a probe. The deduced amino acid sequence of the ORrab2 gene shared all the conserved regions, important for GTPase/GTP binding activities ...
Ho Yeon Kim, Hak Soo Seo, Jin Yong Jeong, Sang Yeol Lee, Moo Je Cho, Jeong Dong Bahk   +5 more
openalex   +3 more sources

Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells

European Journal of Cell Biology, 2000
Rab proteins belong to a subfamily of small GTP-binding protein genes of the Ras superfamily and play an important role in intracellular vesicular targeting. The presence of members of this protein family was examined in Caco-2 cells by a PCR-based strategy.
Frank J.M. Opdam, Gera Kamps, Huib J. E. Croes, Hans van Bokhoven, Leo A. Ginsel, Jack Fransen   +5 more
openalex   +4 more sources

Rab GTPases, tethers, and SNAREs work together to regulate Arabidopsis cell plate formation

Frontiers in Plant Science, 2023
Cell plates are transient structures formed by the fusion of vesicles at the center of the dividing plane; furthermore, these are precursors to new cell walls and are essential for cytokinesis.
Yumei Shi, Changxin Luo, Yun Xiang, Dong Qian   +3 more
doaj   +1 more source

Hepatitis B virus movement through the hepatocyte: An update

Biology of the Cell, Volume 114, Issue 12, Page 325-348, December 2022., 2022
Model of intracellular trafficking routes of progeny hepatitis B virus (HBV) viral and subviral particles through the liver cell involving nucleocytoplasmic shuttling, movement through the ER/Golgi secretory pathway, and budding and release through the multivesicular body (MVB) and/or secretory autophagosomes (sAP) axis.
Reinhild Prange
wiley   +1 more source

Phylogenetic and Expression Studies of Small GTP-Binding Proteins in Solanum lycopersicum Super Strain B

Plants, 2022
This investigation involved a comparative analysis of the small GTPase superfamily in S. lycopersicum super strain B compared to their analogues in leguminous and other non-leguminous species.
H. S. Al-Zahrani, T. Moussa, H. Alsamadany, R. Hafez, M. Fuller   +4 more
semanticscholar   +1 more source

Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells

Scientific Reports, 2021
Rab46 is a novel Ca2+-sensing Rab GTPase shown to have important functions in endothelial and immune cells. The presence of functional Ca2+-binding, coiled-coil and Rab domains suggest that Rab46 will be important for coupling rapid responses to ...
Lucia Pedicini, Sabina D. Wiktor, Katie J. Simmons, Ashley Money, Lynn McKeown   +4 more
doaj   +1 more source

Locations of Rab, Allatotropin, Prothoracicotropic hormone and Period in the larval brain, corpus allatum and frontal ganglion of Bombyx mori

European Journal of Entomology, 2023
Rab, a low molecular weight GTP-binding protein, regulates the transmission of intracellular proteins. Insect neuropeptides that are directly involved in growth, development, reproduction, homeostasis, courtship, feeding, circadian rhythm and many other ...
Asuka MATSUI, Makoto TOKUSHIGE, Akira MIZOGUCHI, Kengo KANAMARU, Katsuhiko SAKAMOTO, Yuichi UNO, Tomohide UNO   +6 more
doaj   +1 more source