Relationship between Rab and insulin-like proteins in the nervous system of Bombyx mori
European Journal of Entomology, 2021 Rab proteins are small GTP-binding proteins and are the largest family in the Ras GTPase superfamily and mediate vesicular transport in cells. Diverse insulin-like peptides, such as bombyxin, are synthesized in the brain and secreted into the haemolymph ...
Tomohide UNO +7 more
doaj +1 more source
Apical transport of influenza A virus ribonucleoprotein requires Rab11-positive recycling endosome. [PDF]
PLoS ONE, 2011 Influenza A virus RNA genome exists as eight-segmented ribonucleoprotein complexes containing viral RNA polymerase and nucleoprotein (vRNPs). Packaging of vRNPs and virus budding take place at the apical plasma membrane (APM).
Fumitaka Momose +6 more
doaj +1 more source
Progress in Fishery Sciences, 2023 The Ras-related proteins in brain (Rab) subfamily is the largest group of small molecule guanine nucleotide-binding regulatory proteins (GTP-binding proteins).
Xinlin SONG +5 more
doaj +1 more source
bMERB domains are bivalent Rab8 family effectors evolved by gene duplication
eLife, 2016 In their active GTP-bound form, Rab proteins interact with proteins termed effector molecules. In this study, we have thoroughly characterized a Rab effector domain that is present in proteins of the Mical and EHBP families, both known to act in ...
Amrita Rai +8 more
doaj +1 more source
Yeast Irc6p is a novel type of conserved clathrin coat accessory factor related to small G proteins. [PDF]
, 2012 Clathrin coat accessory proteins play key roles in transport mediated by clathrin-coated vesicles. Yeast Irc6p and the related mammalian p34 are putative clathrin accessory proteins that interact with clathrin adaptor complexes.
Cascio, Duilio +5 more
core +1 more source
Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2 [PDF]
, 2020 Rab8a is associated with the dynamic regulation of membrane protrusions in polarized cells. Rab8a is one of several Rab GTPases that are substrates of leucine-rich repeat kinase 2 (LRRK2), a serine/threonine kinase that is linked to Parkinson's disease ...
Alessi, Dario R. +5 more
core +3 more sources
This Is the End: Regulation of Rab7 Nucleotide Binding in Endolysosomal Trafficking and Autophagy
Frontiers in Cell and Developmental Biology, 2018 Rab7 – or in yeast, Ypt7p – governs membrane trafficking in the late endocytic and autophagic pathways. Rab7 also regulates mitochondrion-lysosome contacts, the sites of mitochondrial fission.
Christopher Stroupe
doaj +1 more source
A Small Guanosine Triphosphate Binding Protein PagRabE1b Promotes Xylem Development in Poplar
Frontiers in Plant Science, 2021 Rab GTPases are the subfamily of the small guanosine triphosphate (GTP)-binding proteins which participated in the regulation of various biological processes. Recent studies have found that plant Rabs play some specific functions.
Ying-Li Liu +8 more
doaj +1 more source
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]
, 2007 Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Barr, Francis A. +5 more
core +2 more sources
Journal of Lipid Research, 2008 Formation of covalently bound protein adducts with lithocholic acid (LCA) might explain LCA's known carcinogenic properties and hepatotoxicity. We performed studies aimed at isolating and identifying hepatic proteins tagged with LCA, presumably via the ε-
Shigeo Ikegawa +6 more
doaj +1 more source