Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells
Scientific Reports, 2021 Rab46 is a novel Ca2+-sensing Rab GTPase shown to have important functions in endothelial and immune cells. The presence of functional Ca2+-binding, coiled-coil and Rab domains suggest that Rab46 will be important for coupling rapid responses to ...
Lucia Pedicini +4 more
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European Journal of Entomology, 2023 Rab, a low molecular weight GTP-binding protein, regulates the transmission of intracellular proteins. Insect neuropeptides that are directly involved in growth, development, reproduction, homeostasis, courtship, feeding, circadian rhythm and many other ...
Asuka MATSUI +6 more
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Relationship between Rab and insulin-like proteins in the nervous system of Bombyx mori
European Journal of Entomology, 2021 Rab proteins are small GTP-binding proteins and are the largest family in the Ras GTPase superfamily and mediate vesicular transport in cells. Diverse insulin-like peptides, such as bombyxin, are synthesized in the brain and secreted into the haemolymph ...
Tomohide UNO +7 more
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Apical transport of influenza A virus ribonucleoprotein requires Rab11-positive recycling endosome. [PDF]
PLoS ONE, 2011 Influenza A virus RNA genome exists as eight-segmented ribonucleoprotein complexes containing viral RNA polymerase and nucleoprotein (vRNPs). Packaging of vRNPs and virus budding take place at the apical plasma membrane (APM).
Fumitaka Momose +6 more
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Progress in Fishery Sciences, 2023 The Ras-related proteins in brain (Rab) subfamily is the largest group of small molecule guanine nucleotide-binding regulatory proteins (GTP-binding proteins).
Xinlin SONG +5 more
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bMERB domains are bivalent Rab8 family effectors evolved by gene duplication
eLife, 2016 In their active GTP-bound form, Rab proteins interact with proteins termed effector molecules. In this study, we have thoroughly characterized a Rab effector domain that is present in proteins of the Mical and EHBP families, both known to act in ...
Amrita Rai +8 more
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Yeast Irc6p is a novel type of conserved clathrin coat accessory factor related to small G proteins. [PDF]
, 2012 Clathrin coat accessory proteins play key roles in transport mediated by clathrin-coated vesicles. Yeast Irc6p and the related mammalian p34 are putative clathrin accessory proteins that interact with clathrin adaptor complexes.
Cascio, Duilio +5 more
core +1 more source
Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2 [PDF]
, 2020 Rab8a is associated with the dynamic regulation of membrane protrusions in polarized cells. Rab8a is one of several Rab GTPases that are substrates of leucine-rich repeat kinase 2 (LRRK2), a serine/threonine kinase that is linked to Parkinson's disease ...
Alessi, Dario R. +5 more
core +3 more sources
This Is the End: Regulation of Rab7 Nucleotide Binding in Endolysosomal Trafficking and Autophagy
Frontiers in Cell and Developmental Biology, 2018 Rab7 – or in yeast, Ypt7p – governs membrane trafficking in the late endocytic and autophagic pathways. Rab7 also regulates mitochondrion-lysosome contacts, the sites of mitochondrial fission.
Christopher Stroupe
doaj +1 more source
A Small Guanosine Triphosphate Binding Protein PagRabE1b Promotes Xylem Development in Poplar
Frontiers in Plant Science, 2021 Rab GTPases are the subfamily of the small guanosine triphosphate (GTP)-binding proteins which participated in the regulation of various biological processes. Recent studies have found that plant Rabs play some specific functions.
Ying-Li Liu +8 more
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