Results 61 to 70 of about 24,778 (199)
New Phytologist, Volume 250, Issue 2, Page 799-804, April 2026.Summary Plant immunity is complex, and studies of leaf epidermal cells attacked by powdery mildew fungi have been instrumental in revealing how it relies on plant endomembrane trafficking. Immunity against these biotrophic fungi is manifested as cell wall deposits (‘papillae’) and the hypersensitive reaction (HR), both involving plant endomembrane ...
Hans Thordal‐Christensen +3 more
wiley +1 more source
RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]
, 2011 The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski +3 more
core +1 more source
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase [PDF]
, 2017 Parkinson's disease predisposing LRRK2 kinase phosphorylates a group of Rab GTPase proteins including Rab29, within the effector‐binding switch II motif. Previous work indicated that Rab29, located within the PARK16 locus mutated in Parkinson's patients,
Adil R Sarhan +11 more
core +2 more sources
BioEssays, Volume 48, Issue 3, March 2026.Directional intracellular cargo transport is traditionally attributed to motor stepping along stationary microtubule (MT) tracks. We propose a complementary mechanism of cargo co‐migration with moving MTs. This mode requires cargo–MT tethering and directed MT motion.
Chuying Zhou, Mineko Kengaku
wiley +1 more source
Journal of Biological Chemistry, 1989 Seven cDNA clones corresponding to the rab1, rab2, rab3A, rab3B, rab4, rab5, and rab6 genes were isolated from a human pheochromocytoma cDNA library. They encode 23-25 kDa polypeptides which share approximately 30-50% homology and belong to the ras superfamily.
Zahraoui, A. +3 more
openaire +2 more sources
The cytokinesis regulator RacGAP1 is a Rac1‐specific GAP on membranes
Protein Science, Volume 35, Issue 3, March 2026.Abstract Rho family small GTPases are essential for cytokinesis completion. RacGAP1, a dimeric multidomain protein with a lipid‐binding C1 domain and a GTPase‐activating protein (GAP) domain, is a major regulator in this process. However, despite many cellular and biochemical studies, whether RhoA or Rac1 is the actual substrate inactivated by RacGAP1 ...
Pavlina Dubois +5 more
wiley +1 more source
Frontiers in Genetics, 2019 Intracellular vesicle trafficking genes, Rab, encoding small GTP binding proteins, have been well studied in medical research, but there is little information concerning these proteins in plants.
Gulmira Khassanova +13 more
doaj +1 more source
Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p. [PDF]
, 2014 The exocyst serves to tether secretory vesicles to cortical sites specified by polarity determinants, in preparation for fusion with the plasma membrane.
Liu, Dongmei, Novick, Peter
core +1 more source
Small, Volume 22, Issue 16, 17 March 2026.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants [PDF]
, 2009 ACAP-type ARF GTPase activating proteins (ARF-GAPs) regulate multiple cellular processes, including endocytosis, secretion, phagocytosis, cell adhesion and cell migration.
Friml, Jiri +6 more
core +1 more source