Results 91 to 100 of about 78,155 (186)
Periodontology 2000, EarlyView.Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source
, 2012 This unit describes methods to identify proteins interacting with, and regulating, Rab GTPases. Rabs form the largest subgroup of Ras superfamily GTPases, and act as molecular switches controlling the specificity of membrane trafficking.
Lars Langemeyer, Francis A. Barr
core +1 more source
Rabs, Rips, FIPs, and Endocytic Membrane Traffic
The Scientific World Journal, 2003 Rab GTPases, proteins belonging to the Ras-like small GTP-binding protein superfamily, have emerged as master regulators of cellular membrane transport.
Rytis Prekeris
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
RAB-5 and RAB-7 GTPases promote DAF-16 FOXO localization to endosomes.
, 2022 (A-F) Representative confocal images of the intestinal cells of animals expressing DAF-16a::GFP (zIs356) (green) and either RFP::RAB-5 (pwIs480) (A-C) or mCherry::RAB-7 (pwIs429) (magenta) (D- F).
Thomas Liontis (13184383) +7 more
core +1 more source
The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity
The Journal of Physiology, EarlyView.Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas +5 more
wiley +1 more source
, 2012 Rab GTPases cycle between an active GTP-bound form and an inactive GDP-bound form. Rab activation is mediated by a guanine exchange factor (GEF). The hydrolysis of bound GTP is catalyzed by a GTPase activating protein (GAP) resulting in the inactivation ...
Joel R. Ho (157387) +9 more
core +1 more source
Emerging roles of small GTPases in secondary cell wall development
Frontiers in Plant Science, 2014 Regulation of plant cell wall deposition and patterning is essential for the normal growth and development of plants. Small GTPases play pivotal roles in the modulation of primary cell wall formation by controlling cytoskeletal organization and membrane ...
Yoshihisa eOda, Hiroo eFukuda
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier +3 more
wiley +1 more source
Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization
, 2011 The Rab GTPases are the largest family of proteins regulating membrane traffic. Rab proteins form a nidus for the assembly of multiprotein complexes on distinct vesicle membranes to regulate particular membrane trafficking pathways. Recent investigations
Joseph T. Roland +17 more
core +1 more source