Results 101 to 110 of about 78,155 (186)

The specification of geometric edges by a plant Rab gtpase is an essential cell-patterning principle during organogenesis in Arabidopsis [PDF]

open access: yes, 2016
Plant organogenesis requires control over division planes and anisotropic cell wall growth, which each require spatial patterning of cells. Polyhedral plant cells can display complex patterning in which individual faces are established as biochemically ...
Kirchhelle, Charlotte   +23 more
core   +1 more source

Conservation of a synaptic blueprint across the animal kingdom

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Conservation of synaptic nanostructure and function across species. Several components of synaptic organization and function in diverse species shown on the left are largely conserved based on a ‘synaptic blueprint’ or essential framework required to achieve the spatial and temporal fidelity of synaptic transmission.
Aiden J. Houcek, Ege T. Kavalali
wiley   +1 more source

Leishmania major large RAB GTPase is highly immunogenic in individuals immune to cutaneous and visceral leishmaniasis

open access: yesParasites & Vectors, 2017
Background We previously identified a Leishmania (L.) major large RAB GTPase (LmlRAB), a new atypical RAB GTPase protein. It is highly conserved in Leishmania species while displaying low level of homology with mammalian homologues.
Rym Chamakh-Ayari   +5 more
doaj   +1 more source

The functions of Rab GTPases in plant membrane traffic.

open access: yes, 2016
Rab GTPases are important determinants of membrane identity and membrane targeting. Higher plants have evolved a unique set of Rab GTPases that presumably reflects the specific demands of plant cell trafficking.

core   +1 more source

Discovery of novel DENN proteins: implications for the evolution of eukaryotic intracellular membrane structures and human disease

open access: yesFrontiers in Genetics, 2012
The tripartite DENN module, comprised of a N-terminal longin domain, followed by DENN and d-DENN domains, is a GDP-GTP exchange factor (GEFs) for Rab GTPases, which are regulators of practically all membrane trafficking events in eukaryotes.
Dapeng eZhang   +3 more
doaj   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Golgi Inheritance: Rab Rides the Coat-Tails

open access: yes, 2008
SummaryA recent study describes a role for a Rab GTPase previously implicated in endoplasmic reticulum and mitochondrial inheritance and for a COPI coatomer subunit in the targeting of a type V myosin to the late Golgi in ...
Pon, Liza A.
core   +1 more source

The BTB/POZ‐MATH Protein ZmBPM1 Interacts With Autophagy‐related Protein ZmATG6 and Modulates the NLR Protein Rp1‐D21‐Mediated Defense Response in Maize

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Chang‐Xiao Tang   +8 more
wiley   +1 more source

Crystal structures of two forms of the Acanthamoeba polyphaga mimivirus Rab GTPase

open access: yes, 2017
Acanthamoeba polyphaga mimivirus (APMV) is a member of the family of giant viruses, harboring a 1,200 kbp genome within its 700 nm-diameter viral particle.
Jin A You   +13 more
core   +1 more source

Host Factors Involved in the Intracellular Movement of Bamboo mosaic virus

open access: yesFrontiers in Microbiology, 2017
Viruses move intracellularly to their replication compartments, and the newly synthesized viral complexes are transported to neighboring cells through hijacking of the host endomembrane systems.
Chi-Ping Cheng
doaj   +1 more source

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