Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins
Rab GTPases serve as major control elements in the coordination and definition of specific trafficking steps and intracellular compartments. Rab activity is modulated in part by GTPase-activating proteins (GAPs), and many RabGAPs share a Tre-2/Bub2 ...
Gabernet-Castello, Carme +3 more
core +1 more source
Methods for Studying Membrane-Proximal GAP Activity on Prenylated Rab GTPase Substrates. [PDF]
Highland CM, Thomas LL, Fromme JC.
europepmc +1 more source
The atypical Rab GTPase associated with Parkinson's disease, Rab29, is localized to membranes. [PDF]
Nagai-Ito Y +5 more
europepmc +1 more source
Large Rab GTPase Rab44 regulates microtubule-dependent retrograde melanosome transport in melanocytes. [PDF]
Maruta Y, Fukuda M.
europepmc +1 more source
Rab proteins and the compartmentalization of the endosomal system.
Of the approximately 70 human Rab GTPases, nearly three-quarters are involved in endocytic trafficking. Significant plasticity in endosomal membrane transport pathways is closely coupled to receptor signaling and Rab GTPase-regulated scaffolds.
Zerial, M., Wandinger-Ness, A.
core
The Sequential Recruitments of Rab-GTPase Ypt1p and the NNS Complex onto pre-HAC1 mRNA Promote Its Nuclear Degradation in Baker's Yeast. [PDF]
Paira S, Chakraborty A, Das B.
europepmc +1 more source
Methods for Assessing the Regulation of a Kinase by the Rab GTPase Ypt1. [PDF]
Wang J, Wang S, Ferro-Novick S.
europepmc +1 more source
Interactions between Transport Protein Particle (TRAPP) complexes and Rab GTPases in Arabidopsis.
Transport Protein Particle II (TRAPPII) is essential for exocytosis, endocytosis, protein sorting and cytokinesis. In spite of a considerable understanding of its biological role, little information is known about Arabidopsis TRAPPII complex topology and
Kuster, B. +18 more
core +1 more source
Rab GTPase Proteins in Tauopathy (5236)
Objective: To elucidate the role of specific Rab GTPase proteins, Rab8a or Rab35, in tau accumulation and aggregate formation. Background: Alzheimer disease (AD) is characterized by the abnormal deposition of amyloid-beta (Aβ) plaques and tau tangles ...
Ma, Nathaniel +5 more
core +1 more source
Who's in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond. [PDF]
Borchers AC, Langemeyer L, Ungermann C.
europepmc +1 more source

