Results 91 to 100 of about 5,788,022 (129)

Molecular docking insights of Nigella sativa compounds as potential antiviral inhibitory agents against the replication-machinery proteins VPg and RdRP in rabbit hemorrhagic disease virus (RHDV)

Virology Journal
Abstract The Rabbit Hemorrhagic Disease Virus (RHDV) represents a significant threat to rabbit populations globally, affecting both wild and domesticated rabbits, with mortality rates ranging from 50% to 90%. Despite its severity, there is currently no specific treatment available for RHDV.
Afifi, Yousef R., El-akkad, Tamer A., Badr, Omnia A., Ibrahim, Shafik D., Serag, Ahmed M.   +4 more
openaire   +2 more sources

Serosurvey on household contacts of Marburg hemorrhagic fever patients. [PDF]

, 2006
The first major outbreak of Marburg hemorrhagic fever (MHF) outside a laboratory environment occurred in the subdistrict of Watsa, Democratic Republic of Congo, from October 1998 to August 2000.
MULANGU, S, TSHOMBA, A, Muyembe-Tamfum, J. J., Robert Swanepoel, Van der Stuyft, Patrick, Jean-Jacques Muyembe-Tamfum, LIBANDE, ML, Muyembe-Tamfum, Jean-Jacques, SWANEPOEL, R, Matthias Borchert, Kulidri, Amayo, Tshomba, Antoine, MUYEMBE-TAMFUM, JJ, Modeste Lifenya Libande, BORCHERT, M, Antoine Tshomba, Borchert, M., Tshomba, A., Van der Stuyft, P., Libande, M. L., Libande, Modeste Lifenya, Kulidri, A., Amayo Kulidri, Mulangu, Sabue, Mulangu, S., Sabue Mulangu, KULIDRI, A, Swanepoel, R., Patrick Van der Stuyft, Borchert, Matthias, Swanepoel, Robert   +30 more
core   +1 more source

Neofunctionalization of the Sec1 α1,2fucosyltransferase paralogue in leporids contributes to glycan polymorphism and resistance to rabbit hemorrhagic disease virus.

PLoS Pathogens, 2015
RHDV (rabbit hemorrhagic disease virus), a virulent calicivirus, causes high mortalities in European rabbit populations (Oryctolagus cuniculus). It uses α1,2fucosylated glycans, histo-blood group antigens (HBGAs), as attachment factors, with their ...
Kristina Nyström, Joana Abrantes, Ana Margarida Lopes, Béatrice Le Moullac-Vaidye, Stéphane Marchandeau, Jézabel Rocher, Nathalie Ruvoën-Clouet, Pedro J Esteves, Jacques Le Pendu   +8 more
doaj   +1 more source

Detection of rabbit hemorrhagic disease virus (RHDV), genotype GI.1 and GI.2 with a new multiplex real-time RT-qPCR protocol, using the minor capsid VP10 gene

Agricultural Science and Practice
Aim. This study aimed to develop a specific and sensitive multiplex real-time reverse transcription PCR (RT-qPCR) method for the detection and differentiation of rabbit hemorrhagic disease virus (RHDV) genotypes GI.1 and GI.2 circulating in Ukraine, using primers and probes based on the ORF2 gene, encoding the minor capsid protein VP10. Furthermore, to
A.A. Mezhenskyi, O.A. Tarasov, N.A. Mezhenska, S.B. Borovkov, A.O. Mezhenskyi   +4 more
openaire   +1 more source

IDENTIFICATION AND CHARACTERIZATION OF THE CURRENTLY CIRCULATING RABBIT HEMORRHAGIC DISEASE VIRUS ISOLATES [PDF]

Assiut Veterinary Medical Journal
Even among vaccinated rabbits, the virus that causes rabbit viral hemorrhagic disease (RHDV) has been increasing in Egypt recently. So, the current study screened the emergent RHDV of vaccinated and unvaccinated domestic rabbits in some Egyptian ...
DOHA AHMED, SAMAH ALI ABODALAL, MOSTAFA SAIFELDIN, RAGAB IBRAHIM, OMAR AMEN   +4 more
doaj   +1 more source

RPS5 interacts with the rabbit hemorrhagic disease virus 3' extremities region and plays a role in virus replication

, 2020
Rabbit hemorrhagic disease virus (RHDV), a member of Caliciviridae family, causes a highly contagious disease in rabbits. The RHDV replication mechanism is poorly understood due to the lack of a suitable culture system in vitro.
Guo, Hongyuan, Tang, Aoxing, Yang, Hongzao, Qi, Ruibin, Liu, Chuncao, Liu, Guangqing, Miao, Qiuhong, Yuan, Ligang, Zhu, Jie   +8 more
core   +1 more source

Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP60

Virulence
Dendritic cells (DCs) present an ideal target for delivering immunogenic cargo due to their potent antigen-presenting capabilities. This targeting approach holds promise in vaccine development by enhancing the efficiency of antigen recognition and ...
Tian Xia, Xiao Lu, Deming Kong, Tiantian Guo, Yueyi Gao, Lingxiang Xin, Yanping Jiang, Xiaona Wang, Zhifu Shan, Jiaxuan Li, Han Zhou, Wen Cui, Xinyuan Qiao, Lijie Tang, Yijing Li, Li Wang   +15 more
doaj   +1 more source

Detection of rabbit haemorrhagic disease virus (RHDV) in nonspecific vertebrate hosts sympatric to the European wild rabbit (Oryctolagus cuniculus)

, 2017
Since its detection in China in 1984, rabbit haemorrhagic disease (RHD) has been the subject of numerous studies. Yet, the evolutionary origin of rabbit haemorrhagic disease virus (RHDV) is still under debate.
Alda, Fernando, Merchán, Tomás, Rocha, Gregorio   +2 more
core   +1 more source

Horizontal transmissible protection against myxomatosis and rabbit hemorrhagic disease by using a recombinant myxoma virus

, 2000
We have developed a new strategy for immunization of wild rabbit populations against myxomatosis and rabbit hemorrhagic disease (RHD) that uses recombinant viruses based on a naturally attenuated field strain of myxoma virus (MV). The recombinant viruses
Pagès-Manté, A., Blasco Lozano, Rafael, Bárcena, Juan, Morales, Mónica, Boga, José Antonio, Torres, Juan María, Vázquez, B., Parra, Francisco, Sánchez-Vizcaíno, J. M., Lucientes, J.   +9 more
core   +1 more source

Detection of a New Recombinant Rabbit Hemorrhagic Disease Virus 2 in China and Development of Virus-like Particle-Based Vaccine

Viruses
Rabbit hemorrhagic disease virus (RHDV) is a very virulent virus of the genus Lagovirus causing severe and fatal hepatitis in the European rabbit (Oryctolagus cuniculus). RHDV has two distinct genotypes: GI.1 (RHDV) and GI.2 (RHDV2). The first RHDV2/GI.2
Bo Hu, Wenyu Dong, Yanhua Song, Zhiyu Fan, Patrizia Cavadini, Fang Wang   +5 more
doaj   +1 more source