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Vaccination against Rabbit Hemorrhagic Disease Virus 2 (RHDV2) Using a Baculovirus Recombinant Vaccine Provides Durable Immunity in Rabbits. [PDF]
VirusesBosco-Lauth AM +10 more
europepmc +1 more source
Analysis of hemaggulutinating ability of the rabbit hemorrhagic disease virus (RHDV) capsid protein expressed in Escherichia coliopenaire
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Vaccine, 1997
An ALVAC (canarypox)-based recombinant virus ALVAC-RHDV (vCP309) expressing a native rabbit hemorrhagic disease virus (RHDV) capsid protein was derived and assessed for its protective efficacy in rabbits. Protection against a lethal RHDV challenge was demonstrated in rabbits inoculated twice with either high (10(7) p.f.u.) or low (10(5) p.f.u.) doses ...
E Paoletti, Peter W Mason, P W Mason
exaly +3 more sources
An ALVAC (canarypox)-based recombinant virus ALVAC-RHDV (vCP309) expressing a native rabbit hemorrhagic disease virus (RHDV) capsid protein was derived and assessed for its protective efficacy in rabbits. Protection against a lethal RHDV challenge was demonstrated in rabbits inoculated twice with either high (10(7) p.f.u.) or low (10(5) p.f.u.) doses ...
E Paoletti, Peter W Mason, P W Mason
exaly +3 more sources
Vaccine, 2011
This report describes the generation of a new recombinant Orf virus (ORFV; Parapoxvirus) expressing the major capsid protein VP1 (VP60) of the calicivirus, rabbit hemorrhagic disease virus (RHDV). Authentic expression of VP1 could be demonstrated in cells infected with the recombinant D1701-V-VP1 without the need for production of infectious ORFV ...
Horst Schirrmeier +2 more
exaly +3 more sources
This report describes the generation of a new recombinant Orf virus (ORFV; Parapoxvirus) expressing the major capsid protein VP1 (VP60) of the calicivirus, rabbit hemorrhagic disease virus (RHDV). Authentic expression of VP1 could be demonstrated in cells infected with the recombinant D1701-V-VP1 without the need for production of infectious ORFV ...
Horst Schirrmeier +2 more
exaly +3 more sources
Journal of Virological Methods, 2008
Reverse transcriptase polymerase chain reaction (RT-PCR) for the diagnosis of rabbit hemorrhagic disease virus (RHDV) was developed by examining sensitivity and specificity. Samples from rabbits infected with rabbit hemorrhagic disease (RHD) were examined to investigate the distribution of the virus in the body.
Fang Wang, Yuanliang Hu, Deyun Wang
exaly +3 more sources
Reverse transcriptase polymerase chain reaction (RT-PCR) for the diagnosis of rabbit hemorrhagic disease virus (RHDV) was developed by examining sensitivity and specificity. Samples from rabbits infected with rabbit hemorrhagic disease (RHD) were examined to investigate the distribution of the virus in the body.
Fang Wang, Yuanliang Hu, Deyun Wang
exaly +3 more sources
Virus Research, 1996
Calicivirus particles isolated from rabbits suffering from acute RHD were compared with virions found in rabbits with chronic disease. Liver homogenates of rabbits with the protracted disease display no hemagglutinating activity and contain viral particles with diameters of 25-27 nm.
F Weiland
exaly +3 more sources
Calicivirus particles isolated from rabbits suffering from acute RHD were compared with virions found in rabbits with chronic disease. Liver homogenates of rabbits with the protracted disease display no hemagglutinating activity and contain viral particles with diameters of 25-27 nm.
F Weiland
exaly +3 more sources
Vaccine
In recent years, the rabbit hemorrhagic disease virus 2(RHDV GI.2) has rapidly spread worldwide due to its broad natural host range, strong pathogenicity, and significant antigenic differences from the traditional RHDV1 (GI.1). The widespread prevalence of both GI.1 and GI.2 RHDV poses a serious threat to the healthy development of the global rabbit ...
Shanchun Su
exaly +3 more sources
In recent years, the rabbit hemorrhagic disease virus 2(RHDV GI.2) has rapidly spread worldwide due to its broad natural host range, strong pathogenicity, and significant antigenic differences from the traditional RHDV1 (GI.1). The widespread prevalence of both GI.1 and GI.2 RHDV poses a serious threat to the healthy development of the global rabbit ...
Shanchun Su
exaly +3 more sources
Taiwan Veterinary Journal, 2021
The hepatocytes were isolated from the liver of different week-age of healthy rabbits by a single two-stage pass perfusion method and suspended in Hanks’ balanced salt solution (Ca[Formula: see text]-, Mg[Formula: see text]-free). The field strains of RHDV were inoculated into the suspension and incubated for 2 days at 37∘C.
Yong-Mi Pyon +3 more
openaire +1 more source
The hepatocytes were isolated from the liver of different week-age of healthy rabbits by a single two-stage pass perfusion method and suspended in Hanks’ balanced salt solution (Ca[Formula: see text]-, Mg[Formula: see text]-free). The field strains of RHDV were inoculated into the suspension and incubated for 2 days at 37∘C.
Yong-Mi Pyon +3 more
openaire +1 more source
Recombination between G2 and G6 strains of rabbit hemorrhagic disease virus (RHDV) in China
Archives of Virology, 2016Rabbit hemorrhagic disease (RHD) is an acute fatal disease caused by the lagovirus rabbit hemorrhagic disease virus (RHDV), which was first reported in 1984 in China. Genetic characterization of RHDV has demonstrated that two different genogroups (G2 and G6) are present in China.
Bo, Hu +6 more
openaire +2 more sources
Applied Microbiology and Biotechnology, 2015
The VP60 protein of rabbit hemorrhagic disease virus (RHDV) is a structural protein with important roles in viral replication and assembly. In this study, we immunized BALB/c mice with the RHDV-TP strain. Six monoclonal antibodies (mAbs) were selected and characterized by enzyme-linked immunosorbent assay, Western blotting, and indirectly ...
Kong, DeSheng +9 more
openaire +2 more sources
The VP60 protein of rabbit hemorrhagic disease virus (RHDV) is a structural protein with important roles in viral replication and assembly. In this study, we immunized BALB/c mice with the RHDV-TP strain. Six monoclonal antibodies (mAbs) were selected and characterized by enzyme-linked immunosorbent assay, Western blotting, and indirectly ...
Kong, DeSheng +9 more
openaire +2 more sources