Results 41 to 50 of about 69,723 (240)

Oral vaccination of dogs: a well-studied and undervalued tool for achieving human and dog rabies elimination

Veterinary Research, 2018
The mass vaccination of dogs is a proven tool for rabies prevention. Besides parenteral delivery of inactivated vaccines, over the past several decades, several self-replicating biologics, including modified-live, attenuated and recombinant viruses, have
Florence Cliquet, Anne-Laure Guiot, Michel Aubert, Emmanuelle Robardet, Charles E. Rupprecht, François-Xavier Meslin   +5 more
doaj   +1 more source

Evaluation of cost-effective strategies for rabies post-exposure vaccination in low-income countries [PDF]

, 2011
<b>Background:</b> Prompt post-exposure prophylaxis (PEP) is essential in preventing the fatal onset of disease in persons exposed to rabies.
Hampson Katie, Katie Hampson, Briggs Deborah, Cleaveland, Sarah, Sarah Cleaveland, Briggs, Deborah, Deborah Briggs, Hampson, Katie, Cleaveland Sarah   +8 more
core   +1 more source

Long-Term Immunogenicity and Efficacy of the Oral Rabies Virus Vaccine Strain SPBN GASGAS in Foxes

Viruses, 2019
To evaluate the long-term immunogenicity of the live-attenuated, oral rabies vaccine SPBN GASGAS in a full good clinical practice (GCP) compliant study, forty-six (46) healthy, seronegative red foxes (Vulpes vulpes) were allocated to two treatment groups:
Conrad M. Freuling, Verena te Kamp, Antonia Klein, Maria Günther, Luca Zaeck, Madlin Potratz, Elisa Eggerbauer, Katharina Bobe, Christian Kaiser, Antje Kretzschmar, Steffen Ortmann, Peter Schuster, Adriaan Vos, Stefan Finke, Thomas Müller   +14 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Dog demography, animal bite management and rabies knowledge-attitude and practices in the Awash Basin, Eastern Ethiopia [PDF]

, 2016
Rabies is a viral zoonosis that has been described in limited numbers of studies in Ethiopia at large and among pastoralists in particular. This study assessed dog demography, bite wound prevalence and management, potential risk factors of disease ...
Bekele, Shiferaw, Aseffa, Abraham, Rea Tschopp, Shiferaw Bekele, Abraham Aseffa, Tschopp, Rea   +5 more
core   +2 more sources

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

Evaluation of a portable multiplex real-time pcr assay for the detection of monkeypox virus and non-variola orthopoxviruses

Virology Journal
Monkeypox (mpox) is the most significant orthopoxvirus (OPXV) infection in humans since smallpox eradication. The World Health Organization (WHO) has twice declared public health emergency of international concern due to the expansive spread of clade I ...
Shanshan Li, Nabojeet Das, Natalie Miller, Ariel Caudle, Kimberly Wilkins, Theodora Khan, Stefan Pfotenhauer, Amy Saunders, Christina L. Hutson, Kodumudi S. Venkateswaran, William M. Nelson, Neeraja Venkateswaran, Panayampalli S. Satheshkumar, Michael B. Townsend   +13 more
doaj   +1 more source

Detection of rabies antibodies in wild boars in north-east Romania by a rabies ELISA test

BMC Veterinary Research, 2019
Background In the last few decades, Romania has been considered one of the European countries most affected by animal rabies, but a combination of oral rabies vaccination (ORV) campaigns in foxes alongside mandatory vaccination of pets has substantially ...
Mihaela Anca Dascalu, Marine Wasniewski, Evelyne Picard-Meyer, Alexandre Servat, Florentina Daraban Bocaneti, Oana Irina Tanase, Elena Velescu, Florence Cliquet   +7 more
doaj   +1 more source

Domestic dog demographic structure and dynamics relevant to rabies control planning in urban areas in Africa: the case of Iringa, Tanzania [PDF]

, 2012
<p>Background Mass vaccinations of domestic dogs have been shown to effectively control canine rabies and hence human exposure to rabies. Knowledge of dog population demography is essential for planning effective rabies vaccination programmes ...
Kazwala Rudovick R, Kazwala, R. R., Penelope Vounatsou, Kazwala, Rudovick R., Vounatsou Penelope, Gsell, A.S., Kazwala, R.R., Zinsstag Jakob, Vounatsou, P., Knobel Darryn L, Cleaveland, S., Darryn L Knobel, Alena S Gsell, Kazwala, R. R., Gsell, A. S., Gsell, Alena S., Zinsstag, Jakob, Knobel, D.L., Gsell Alena S, Knobel, D. L., Rudovick R Kazwala, Jakob Zinsstag, Knobel, Darryn Leslie, Vounatsou, Penelope, Zinsstag, J.   +24 more
core   +2 more sources