Results 51 to 60 of about 43,348 (195)

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

Interdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang, Junge Chen, Jiao Xia, Weitong Yang, Teng Ma, Tianzi Shan, Weifeng He, Gaoman Zhang, Zhuoran Xia, Weiwei Wang, Zhusheng Liu, Zhiqiang Yi, Piye Niu, Tian Chen   +13 more
wiley   +1 more source

Inactivated Rabies Virus-Vectored Immunocontraceptive Vaccine in a Thermo-Responsive Hydrogel Induces High and Persistent Antibodies against Rabies, but Insufficient Antibodies against Gonadotropin-Releasing Hormone for Contraception

Vaccines, 2019
Rabies is preventable through vaccination, but the need to mount annual canine vaccination campaigns presents major challenges in rabies control and prevention.
Xianfu Wu, Yong Yang, Chantal Kling, Laurie Seigler, Nadia F. Gallardo-Romero, Brock E. Martin, Todd G. Smith, Victoria A. Olson   +7 more
doaj   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

Mathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang, Yaya Wang, Hongyin Geng, Wei Gao, Esin Ilhan, Haci Mehmet Baskonus   +5 more
wiley   +1 more source

Längerlebige Loch‐Qubits durch stärkere Spin‐Bahn‐Kopplung: Schneller treiben, länger leben

Physik in unserer Zeit, EarlyView.
Halbleiter‐Spin‐Qubits in Quantenpunkten stehen vor dem vermeintlichen Dilemma, dass schnelle Spin‐Kontrolle durch stärkere Kopplung an das Umfeld nur auf Kosten der Kohärenz möglich ist. Da deren Eigenschaften empfindlich vom einbettenden elektrostatischen Potential abhängen, lässt sich dieser Gegensatz durch eine gezielte Feinabstimmung des ...
Miguel J. Carballido
wiley   +1 more source

Impact of general anaesthesia on immune response to first rabies vaccination in seronegative domestic cats

Veterinary Record, EarlyView.
Abstract Background Despite common concerns, evidence that anaesthesia impairs vaccine efficacy remains limited. This study assessed the impact of general anaesthesia on the immune response to rabies vaccination in cats. Methods Thirty‐five healthy female cats (6–12 months old) undergoing elective spaying were enrolled.
Pierre Bessière, Romane Breysse, Marion Chrétien, Brandon Hayes, Séverine Boullier, Anouck Labadie, Jonathan Rieder, Marine Wasniewski, Géraldine Jourdan   +8 more
wiley   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source

Citizen science project on urban canids provides different results from camera traps but generates interest and revenue

Wildlife Biology, EarlyView.
As urbanization increases, wildlife increasingly encounters people. Coyotes Canis latrans and red foxes Vulpes vulpes are two canid species that have readily adapted to urban environments. Citizen science has emerged as a low‐cost method of collecting data on urban‐adapted species that can benefit management agencies but may provide different results ...
Neville F. Taraporevala, Jon P. Beckmann, Julie K. Young   +2 more
wiley   +1 more source

Ecology of declining populations of gray foxes (Urocyon cinereoargenteus) in Indiana, USA Ecología de las poblaciones en declive de zorros grises (Urocyon cinereoargenteus) en Indiana, EE.UU.

Wildlife Monographs, EarlyView.
We estimated seasonal space use, cover selection, and resource selection; evaluated gene flow and potential genetic barriers; and assessed cause‐specific survival rates and reproduction of radiomarked gray foxes in Indiana, USA. Our results provide evidence that gray foxes in Indiana are an edge species with relatively large home ranges, relatively low
Tim L. Hiller, Julia A. Nawrocki, Brandon M. Bernhardt, Lane K. Jeakle, Dawn M. Reding, Geriann Albers   +5 more
wiley   +1 more source

A retrospective study of rabies in puppies in Nigeria, 2012-2021

The Proceedings of the Nigerian Academy of Science
Rabies has no cure and this makes it one of the most fatal zoonotic diseases known to mankind. It is caused by a rabies virus in the genus Lyssavirus and family Rhabdoviridae.
Leviticus Konzing, Ishaya S. Tekki, Sunday E. Hambolu, Ponfa N. Zhakom, Clement J. Livinus, Joseph A. Davou, Rabo S. Haruna, Preciuos N. Lombin, Clement A. Meseko   +8 more
doaj   +1 more source

Diagnosis and Analysis of a Recent Case of Human Rabies in Canada

Canadian Journal of Infectious Diseases, 2002
BACKGROUND: On September 30, 2000, staff at the Canadian Food Inspection Agency's Centre of Expertise for Rabies, located at the Animal Diseases Research Institute in Ottawa, Ontario, diagnosed rabies in a child from Quebec.
Lindsay D Elmgren, Susan A Nadin-Davis, Frances T Muldoon, Alexander I Wandeler   +3 more
doaj   +1 more source