Results 171 to 180 of about 131,005 (322)
Neoplasia, 2012 We report that Binder of Arl Two (BART) plays a role in inhibiting cell invasion by regulating the activity of the Rho small guanosine triphosphatase protein Rac1 in pancreatic cancer cells. BART was originally identified as a binding partner of ADP-ribosylation factor-like 2, a small G protein implicated as a regulator of microtubule dynamics and ...
Keisuke Taniuchi +2 more
openaire +3 more sources
Linking Superoxide Production and Scavenging in Plant Development
Plant, Cell &Environment, EarlyView.ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
wiley +1 more source
Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling [PDF]
, 2002 Shuichi Furuta +5 more
openalex +1 more source
Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration
Oncology Letters, 2018 The ability of tumor cells to migrate is biologically fundamental for tumorigenesis, growth, metastasis and invasion. The present study examined the role of Ras-related C3 botulinum toxin substrate (RAC1) and vasodilator-stimulated phosphoprotein (VASP ...
Yihao Tian +8 more
semanticscholar +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
Photochemistry and Photobiology, EarlyView.The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Prior studies have investigated the efficacy of a single 1 min bout of stair‐stepping on reducing postprandial blood glucose (BG) in the morning, but none have investigated this effect in the evening when glycaemic responses are larger due to circadian regulation and β‐cell responsiveness. This work investigated the efficacy of a 1 min bout of
Austin Morales +3 more
wiley +1 more source
A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy. [PDF]
, 1998 J.B. Pracyk +12 more
openalex +1 more source
In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells
Experimental Physiology, EarlyView.Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene +4 more
wiley +1 more source