Results 151 to 160 of about 83,967 (245)

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 6, Page 729-747, September 2026.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Staurosporine Drives Non‐Canonical Melanocyte Maturation by Coupling β‐Catenin Signaling to Actin‐Dependent Dendrite Remodeling

Pigment Cell &Melanoma Research, Volume 39, Issue 5, September 2026.
Staurosporine drives non‐canonical melanocyte maturation through β‐catenin‐dependent actin remodeling. Functional maturation enhances dendrite architecture and melanogenic differentiation without inducing melanocyte proliferation, providing a biological framework for restoring functional melanocytes in acquired hypopigmentary disorders.
Kangning Xu, Lingli Yang, Sylvia Lai, Fei Yang, Yasutaka Kuroda, Daisuke Tsuruta, Ichiro Katayama   +6 more
wiley   +1 more source

Audioteca de RAC1

, 2016
És una aplicació que dona suport a la nova web de RAC 1, gestionant les parts que el CMS web no pot fer o li és complicat. Gestiona els fitxers àudio en format MP3, permet la seva cerca, la gestió de programes i graelles, dona suport a l'app, RSS/Podcast.
openaire   +1 more source

Targeting RAC1 in glioblastoma: prognostic value, immune landscape, and small molecule therapeutic potential. [PDF]

Front Oncol
Wu Q, Chen S, Xie X, Feng X, Zhang Z, Su G.   +5 more
europepmc   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

IAPs targeting RAC1 [PDF]

Nature Reviews Molecular Cell Biology, 2011
openaire   +1 more source

The Involvement of the Small GTPase Rac1 in Insulin Signaling That Regulates Plasma Membrane Translocation of the Fatty Acid Transporter CD36 in Mouse White Adipocytes. [PDF]

Int J Mol Sci
Takenaka N, Sakata M, Abe Y, Iha K, Satoh T.   +4 more
europepmc   +1 more source

Characterization of Ovarian Cell Types and Molecular Signatures in Mauremys reevesii Using Single‐Cell Sequencing

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
This study employed single‐cell transcriptomics to identify six major cell types in the Mauremys reevesii ovary. Except for an unknown cell group, five cell types, including oocytes, granulosa cells, fibroblasts, immune cells, and endothelial cells, were characterized with specific marker genes.
Kaiqi Yuan, Xin Niu, Yue Yuan, Jiale Zhou, Meiling Hong, Li Ding   +5 more
wiley   +1 more source

Qishen Granules attenuate adverse ventricular remodeling in chronic heart failure by promoting Legumain/Arg1/Rac1-mediated efferocytosis of resident cardiac macrophages. [PDF]

Chin Med
Tao M, Min S, Liu J, Xiao H, Xiao T, Liang S, Liu X, Wang J, Ouyang Y, Wen R, Wang L, Wang W, Zhang Y, Li C.   +13 more
europepmc   +1 more source