Results 51 to 60 of about 993 (170)

Persistent diarrhea: still an important challenge for the pediatrician [PDF]

, 2011
OBJECTIVE: To provide recent guidelines to reduce the incidence of diarrheal diseases. We discuss the definition, clinical aspects, pathophysiology, diagnosis, management, and prevention of persistent diarrhea.
Andrade, Jacy Alves Braga de, Fagundes-Neto, Ulysses   +1 more
core   +1 more source

Multivariate Optimization of Chromatographic Conditions for Rapid Simultaneous Quantification of Antidiarrheal Drugs in Formulation Using Surface Response Methodology

Separations, 2022
A combination of antibiotics and antiprotozoal and antisecretory medicines has been prescribed for the treatment of diarrhea. A rapid, reproducible liquid chromatographic procedure was established for the concurrent analysis of metronidazole (MET ...
Mahesh Attimarad, Katharigatta Narayanaswamy Venugopala, Muhammad S. Chohan, Pottathil Shinu, Marysheela David, Effren II Plaza Molina, Anroop Balachandran Nair, Nagaraja Sreeharsha, Abdulrahman Ibrahim Altaysan, Abdulmalek Ahmed Balgoname   +9 more
doaj   +1 more source

Xyloglucan for the treatment of acute diarrhea: results of a randomized, controlled, open-label, parallel group, multicentre, national clinical trial [PDF]

, 2015
Background: There is a strong rationale for the use of agents with film-forming protective properties, like xyloglucan, for the treatment of acute diarrhea. However, few data from clinical trials are available.
Lucio Gnessi, Marius Marusteri, Núria Piqué, Vladimir Bacarea   +3 more
core   +2 more sources

Racecadotril versus placebo in the treatment of acute diarrhoea in adults [PDF]

Alimentary Pharmacology & Therapeutics, 1999
MethodsA two‐centre, double‐blind, parallel‐group, randomized study was carried out to compare the efficacy and tolerability of racecadotril (100 mg three times daily) and placebo in 70 adult patients with acute diarrhoea. An objective criterion of antisecretory activity, stool weight, was used.ResultsRacecadotril produced a significant (P = 0.025 ...
H. Ben Khalifa, H. Hamza, Jeanne-Marie Lecomte, P. Baumer, H. Berard   +4 more
openaire   +3 more sources

FORMULATION AND EVALUATION OF RACECADOTRIL MUCOADHESIVE MICROSPHERES

International Journal of Pharmacy and Pharmaceutical Sciences, 2019
Objective: To develop and evaluate the mucoadhesive microsphere using combinations of natural polymers chitosan and xanthan gum for sustained release. Methods: In the present work mucoadhesive microspheres were prepared by using natural polymers like chitosan and xanthan gum by using the emulsion chemical cross-linking method.
Nikhil Kumbhar, Kanchan Jamkar, Sharwaree Hardikar, Swati Mutha   +3 more
openaire   +3 more sources

Pathogenetic Mechanisms of Diarrhea in Children and Methods for Its Treatment

Zdorovʹe Rebenka, 2014
The paper presents the current views on the pathogenesis of acute intestinal infections in children and principles of therapy of diarrhea syndrome. Particular attention is paid to antisecretory therapy and the role of racecadotril in relieving diarrhea.
B.I. Krivuschev
doaj   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang, Theng Yi Tay, Simon Gibbs, Ola Niewiadomski   +3 more
wiley   +1 more source

Chronic diarrhoea in children. [PDF]

, 2012
Chronic diarrhoea in children shows an age related spectrum. In infants and young children a major role is related to persistent intestinal infections, intolerance to specific nutrients such as cow's milk protein, and toddler's diarrhoea.
BERNI CANANI, ROBERTO, GUARINO, ALFREDO, LO VECCHIO, ANDREA   +2 more
core   +1 more source

The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea. [PDF]

, 2019
PurposeDiarrhea is recognized as a common adverse event associated with tyrosine kinase inhibitors (TKIs), with those targeting the ErbB family of receptors being associated with the highest rate of diarrhea.MethodsThis paper reviews data on the ...
Bosserman, Linda, Bryce, Richard, Di Palma, Jack A, Moran, Susan, Olek, Elizabeth, Rugo, Hope S, Tripathy, Debu   +6 more
core  

Hereditary angioedema in children: Review and practical perspective for clinical management

Pediatric Allergy and Immunology, Volume 35, Issue 12, December 2024.
Abstract Background Hereditary angioedema (HAE) in children has specific features and requires multidisciplinary management. Methods We performed a literature search and underwent in‐depth discussions to provide practical tools for physicians. Results HAE is a rare, life‐threatening genetic disorder.
Anne Pagnier, Angelina Dermesropian, Charlotte Kevorkian‐Verguet, Mélisande Bourgoin‐Heck, Cyrille Hoarau, Héloïse Reumaux, Frédérique Nugues, Christine Audouin‐Pajot, Sibylle Blanc, Aurélia Carbasse, Anne‐Laure Jurquet, Mélanie Voidey, Mona Villedieu, Laurence Bouillet, Isabelle Boccon‐Gibod   +14 more
wiley   +1 more source