Results 61 to 70 of about 1,478 (205)

Kein Effekt von Laktobazillus und Racecadotril [PDF]

Pädiatrie, 2009
Zwei aktuelle Studien gingen der Frage nach, ob bei einer akuten Gastroenteritis neben der Rehydratiation auch andere Therapieoptionen eine relevante Wirkung haben.
openaire   +1 more source

Comparison of racecadotril and loperamide in children with acute diarrhoea [PDF]

Alimentary Pharmacology & Therapeutics, 1999
MethodsA multicentre, parallel‐group, double‐blind, double‐placebo study was carried out to compare the efficacy, tolerability, and safety of racecadotril and loperamide in children aged 2 to 10 years who were suffering from acute diarrhoea. Patients received racecadotril (1.5 mg/kg) or loperamide (0.03 mg/kg) three times daily plus matching placebo ...
D, Turck, H, Berard, N, Fretault, J M, Lecomte   +3 more
openaire   +2 more sources

COMPARISON OF RACECADOTRIL WITH ORAL REHYDRATION SOLUTION IN ACUTE WATERY DIARRHEA UNDER 5 YEARS OF AGE

Pakistan Postgraduate Medical Journal, 2022
BACKGROUND: A significant share (18%) of paediatric mortality is caused by diarrheal diseases. Children under the age of five are most susceptible to viral diarrhoea.
Amir Rashid, Nazia Zaib, Anum Arshad, Muhammad Adil Khan   +3 more
semanticscholar   +1 more source

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu, Yuxin Qiu, Guzhong Chen, Wenyao Chen, Xiang Zhang, Zhiwen Qi, Xuezhi Duan, De Chen, Zhen Song   +8 more
wiley   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

Journal of Gastroenterology and Hepatology, Volume 40, Issue 12, Page 2842-2856, December 2025.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang, Theng Yi Tay, Simon Gibbs, Ola Niewiadomski   +3 more
wiley   +1 more source

Development and Validation of a High Performance Liquid Chromatography Method for the Determination of Bromopride in the Presence of Methylparaben and Propylparaben in Pharmaceutical Formulations

SEPARATION SCIENCE PLUS, Volume 8, Issue 11, November 2025.
ABSTRACT A reversed‐phase high‐performance liquid chromatography method was developed and validated for the determination of bromopride (BROP) in the presence of methylparaben and propylparaben, using isocratic mode, C18 chromatographic column, mobile phase composed of acetonitrile and aqueous phase previously acidified with phosphoric acid to pH 3.5 ...
Francielli Gelatti Bortoly Carvalho, Patrícia Espinosa dos Santos, Elaine de Oliveira Araújo, Marcos Serrou do Amaral, Teófilo Fernando Mazon Cardoso, Nájla Mohamad Kassab   +5 more
wiley   +1 more source

Evaluating the cost utility of racecadotril for the treatment of acute watery diarrhea in children: the RAWD model

ClinicoEconomics and Outcomes Research, 2012
Tamlyn Anne Rautenberg1,2, Ute Zerwes1, Douglas Foerster3,4, Rick Aultman51Assessment in Medicine GmbH, Lörrach, Germany; 2Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom; 3Abbott Products Operations AG, Allschwil,
Rautenberg TA, Zerwes U, Foerster D, Aultman R   +3 more
doaj  

Opioid Facilitation of β-Adrenergic Blockade: A New Pharmacological Condition?

Pharmaceuticals, 2015
Recently, propranolol was suggested to prevent hyperlactatemia in a child with hypovolemic shock through β-adrenergic blockade. Though it is a known inhibitor of glycolysis, propranolol, outside this observation, has never been reported to fully protect ...
Joseph Vamecq, Karine Mention-Mulliez, Francis Leclerc, Dries Dobbelaere   +3 more
doaj   +1 more source

Enhancement of Dissolution Rate of Olmesartan Medoxomil Using Urea as Carrier by Different Solid Dispersion Techniques [PDF]

, 2018
The poor solubility of drug substances in water and their low dissolution rate in aqueous G.I.T fluid often leads to insufficient bioavailability. As per Biopharmaceutical Classification System (BCS), Olmesartan belongs to the class-II category having ...
Gomathi, M. (M), Sangameswaran, B. (B)
core  

Drug prescribing pattern in acute gastroenteritis in an in-patient setting in a private hospital [PDF]

, 2017
Background: Diarrheal diseases cause significant morbidity in developing countries and are the leading cause of death in children. The study was undertaken to assess drug utilization patterns in patients with gastroenteritis in a private setting.Methods:
Bhaveshaikh, Nachiket, Sukumaran, Sangita, Vyas, Upal   +2 more
core   +2 more sources