Results 61 to 70 of about 993 (170)

Drug prescribing pattern in acute gastroenteritis in an in-patient setting in a private hospital [PDF]

, 2017
Background: Diarrheal diseases cause significant morbidity in developing countries and are the leading cause of death in children. The study was undertaken to assess drug utilization patterns in patients with gastroenteritis in a private setting.Methods:
Bhaveshaikh, Nachiket, Sukumaran, Sangita, Vyas, Upal   +2 more
core   +2 more sources

Patch tests in non‐immediate cutaneous adverse drug reactions: Late readings on Day 4 is more sensitive than on Day 3

Contact Dermatitis, Volume 91, Issue 4, Page 321-326, October 2024.
Our study shows that a second reading at D4 (24.9%) enchances the sensitivity of a first reading at D3 (13.7%) for the patients' positivity of PTs with suspect drugs in the exploration of NICADR (p < 0.0001). Late readings should not be carried out on D3 because of an important loss of sensibility compared to D4.
Ilaria Matei, Thomas Bettuzzi, Amandine Weill, Gwendeline Gener, Kamar Bel Hareth, Fleck Margaux, Muriel Verlinde‐Carvalho, Muriel Paul, Saskia Ingen‐Housz‐Oro, Haudrey Assier   +9 more
wiley   +1 more source

Long term outcomes in children with trichohepatoenteric syndrome

American Journal of Medical Genetics Part A, Volume 194, Issue 2, Page 141-149, February 2024.
Abstract Trichohepatoenteric syndrome (THES) is a rare autosomal recessive disorder caused by mutations in either TTC37 or SKIV2L, usually leading to congenital diarrhea as part of a multisystem disease. Here, we report on the natural history of the disease for the largest UK cohort of patients with THES from 1996 to 2020.
Kwang Yang Lee, Ronald Bremner, Jane Hartley, Sue Protheroe, Wolfram Haller, Tracey Johnson, Lisa Whyte   +6 more
wiley   +1 more source

Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5FU failure [PDF]

, 2000
Our purpose was to determine, in patients with metastatic colorectal carcinoma treated with irinotecan single-agent after 5-FU failure, the most significant predictive parameters for tumour response, progression-free survival and toxicity.
Awad, L, Bleiberg, H, Bugat, R, Culine, S, Droz, J-P, Freyer, G, Herait, P, Marty, M, Mignard, D, Rougier, P, Trillet-Lenoir, V   +10 more
core   +2 more sources

Protein Kinase Inhibitors Indicated for Lung Cancer: Pharmacodynamics, Pharmacokinetics, Adverse Drug Reactions, and Evaluation in Clinical Trials

Journal of Clinical Pharmacy and Therapeutics, Volume 2024, Issue 1, 2024.
WhatIs Known and Objective. Anti‐EGFR (epidermal growth factor receptor) drugs are indicated for non‐small‐cell lung cancer (NSCLC). This review summarises the information available to date on the first anti‐EGFRs granted market authorisation: erlotinib TARCEVA®, gefitinib IRESSA®, afatinib GIOTRIF®, dacomitinib VIZIMPRO®, and osimertinib TAGRISSO ...
Constance Bordet, Vincent Dongay, Yoann Zelmat, Julien Mazieres, Fabien Despas, Samuel Silvestre   +5 more
wiley   +1 more source

Opioid Facilitation of β-Adrenergic Blockade: A New Pharmacological Condition?

Pharmaceuticals, 2015
Recently, propranolol was suggested to prevent hyperlactatemia in a child with hypovolemic shock through β-adrenergic blockade. Though it is a known inhibitor of glycolysis, propranolol, outside this observation, has never been reported to fully protect ...
Joseph Vamecq, Karine Mention-Mulliez, Francis Leclerc, Dries Dobbelaere   +3 more
doaj   +1 more source

Racecadotril: new acute diarrhoea treatment for adults and children [PDF]

Prescriber, 2013
AbstractRacecadotril (Hidrasec) is a new class of drug for the treatment of acute diarrhoea. In our New products review, Steve Chaplin presents the clinical data relating to its efficacy and adverse events, and Drs Al‐Hilou, Patel and Wilkinson discuss its place in therapy.
Hossam Al-Hilou, Kamal V. Patel, Mark Wilkinson, Steve Chaplin   +3 more
openaire   +2 more sources

Evaluating the cost utility of racecadotril for the treatment of acute watery diarrhea in children: the RAWD model

ClinicoEconomics and Outcomes Research, 2012
Tamlyn Anne Rautenberg1,2, Ute Zerwes1, Douglas Foerster3,4, Rick Aultman51Assessment in Medicine GmbH, L&ouml;rrach, Germany; 2Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom; 3Abbott Products Operations AG, Allschwil,
Rautenberg TA, Zerwes U, Foerster D, Aultman R   +3 more
doaj  

Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children

International Journal of Pediatrics, 2013
Acute diarrhoea is a leading cause of child mortality in developing countries. Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation.
Christophe Faure
doaj   +1 more source

Use (or Misuse) of Drugs in Pediatrics [PDF]

, 2011
Introdução e Objectivos: A exposição a fármacos na idade pediátrica pode ser nociva. A utilização elevada de medicamentos não aprovados em Pediatria, bem como o uso para sintomas em que a sua eficácia não foi comprovada, tem sido descrita de forma ...
Almeida, H, Brito, MJ, Luís, C, Maia, R, Moura, M, Ribeiro, R   +5 more
core