Results 191 to 200 of about 89,874 (280)

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

An HPLC-MS-Based Method for Determination of the D- and L- 5-Methyltetrahydrofolate Isomer Ratio in Dietary Supplements. [PDF]

J AOAC Int
Wang X, Pandey D, Vavilala S, Oh L, Gusev P, Andrews KW, Pehrsson P, Harnly JM, Sun J.   +8 more
europepmc   +1 more source

Racemic drugs: racemic mixture, racemic compound, or pseudoracemate?

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2000
openaire   +1 more source

Unveiling Value in Plastic Waste: Synthesis of 1,3‐Dioxolan‐4‐ones from Polylactic Acid and Polyoxymethylene to Enhance Plastic Biodegradation

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
An acid‐catalyzed process provides a robust method to upcycle even impure and colored PLA and POM plastic waste into high‐value DOXs. Incorporating these DOXs enables the synthesis of PLLA materials that exhibit enhanced biodegradability, surpassing the performance of cellulose.
Mi‐hyun Lee, Joohyun Park, Hyeongyeong Lee, Woo Yeon Cho, Semin Son, Pyung Cheon Lee, In‐Hwan Lee, Hye‐Young Jang   +7 more
wiley   +1 more source

Synergistic diselenide/guanidine catalyzed dehydrophosphorylation of 2-nitrobenzhydrols to access C-stereogenic phosphinates. [PDF]

Chem Sci
Gong JY, Zhou PP, Qiao YH, Qi ZC, Zuo QM, Fang QX, Yang SD.   +6 more
europepmc   +1 more source

Substitutive Approach Toward Heteroaromatic Amino Alcohols Accessed Through Dioxolanyl Radical Linchpin

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
A dioxolanyl linchpin has been used to synthesize aryl ethanolamines from readily available aryl bromide and amine starting materials using a metallaphotoredox/substitution telescoped sequence. This combinatorial approach allows for a wide synthetic scope of both heteroarenes and cyclic amines. Aryl ethanolamines are an important functional group found
Justin J. Chang, Munnu Kumar, Ryan C. Kashatus, Dylan J. Tomaselli, Daniel K. Kim   +4 more
wiley   +1 more source

Porous organic cage mixed matrix membranes for efficient enantioseparation. [PDF]

Nat Commun
Li Y, Liu Z, Zhu D, Xia Y, Wu B, Xu T, Li X, Xu T.   +7 more
europepmc   +1 more source

Synthesis and Characterization of Pyridine‐Ligated Bicyclic (Alkyl)(Amino)Carbene (BICAAC) Ruthenium Alkylidene Complexes

ChemCatChem, Volume 18, Issue 7, 14 April 2026.
First synthesis and comprehensive characterization of pyridine‐ligated BICAAC–Ru benzylidene complexes. The compounds were obtained using a modified Grubbs protocol that prevents bis‐carbene formation, starting from in situ generated BICAAC ligands and bis‐pyridine ruthenium phosphine intermediates.
Pooja Dubey, Ádám Erdélyi, Márton Nagyházi, Gábor Turczel, Attila Bényei, Tibor Nagy, Sándor Kéki, Robert Tuba   +7 more
wiley   +1 more source

Influence of Conspecific Male Odour and Host Kairomones on the Behaviour of Sternochetus mangiferae, a Pest of Mangoes in Brazil and Ghana. [PDF]

J Chem Ecol
Borges M, Michereff MFF, Laumann RA, Vuts J, Hassemer MJ, Machado JVC, Aquino MFS, Leite KKS, de Carvalho Silva A, Ricalde MP, Braimah H, Birkett MA, Blassioli-Moraes MC.   +12 more
europepmc   +1 more source

Unlocking the Synthetic Potential of HMF Derivatives in Catalytic Asymmetric Aza‐Piancatelli Rearrangement

ChemistryEurope, Volume 4, Issue 4, April 2026.
5‐Hydroxymethylfurfural (HMF) derivatives have been successfully transformed via asymmetric aza‐Piancatelli rearrangement catalyzed by a chiral phosphoric acid. This work constitutes the first example of asymmetric Piancatelli rearrangement on C‐5 substituted (2‐furyl)carbinols and its application to HMF derivatives, effectively unlocking the latent ...
Clémentine Mayet, Thibault Mattera, Pascal Retailleau, Jean‐François Betzer   +3 more
wiley   +1 more source