Results 201 to 210 of about 89,874 (280)

Stereoconvergent Photo-Biocatalytic Cascade to Optically Enriched Amines from Racemic Carboxylic Acids. [PDF]

ACS Omega
Rudzka A, Madej A, Reiter T, Kroutil W, Borowiecki P.   +4 more
europepmc   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Spontaneous Mirror-Symmetry Breaking Destabilizes Racemates: A Route to Homochirality and Reversed Chemical Selectivity. [PDF]

Chemphyschem
Ribó JM, Micheau JC, Buhse T.
europepmc   +1 more source

Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT Hexahydroquinoline (HHQ) is a widely recognized scaffold that has garnered considerable attention owing to its diverse pharmacological properties. The structure of HHQ includes a 1,4‐dihydropyridine (DHP) ring, which serves as the pharmacophore for the predominant class of drugs known as calcium channel blockers.
Ebru Koçak Aslan, Kevin Lam, Sun Huang, Göknil Pelin Coşkun, Ayşe Karagüzel, Katrin Denzinger, Kaan Birgül, Mert Ülgen, Jordan W. Nafie, Onur Şahin, Daniel W. Armstrong, Gerald W. Zamponi, Gerhard Wolber, Miyase Gözde Gündüz   +13 more
wiley   +1 more source

Chiral Recognition Mechanism of 2,13-Bis(hydroxymethyl)-[7]thiaheterohelicene on Ag(111) Investigated by STM and MD Simulation. [PDF]

Int J Mol Sci
Ye C, Hattori T, Hamamoto Y, Krukowski P, Saito A, Osuga H, Morikawa Y, Kuwahara Y.   +7 more
europepmc   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Discovery of VU6083859, a TAOK1 Selective Inhibitor, and VU6080195, a <i>pan</i>-TAOK Activator. [PDF]

ACS Chem Neurosci
Schultz DC, Parr LC, Sweet H, Lamb S, Engers JL, Napier NC, McKinnie HG, Whomble D, Kramlinger V, Boutaud O, Lindsley CW.   +10 more
europepmc   +1 more source

Analytical Challenges in Detecting New Psychoactive Substances in Anti‐Doping: A Proof‐of‐Concept Involving Pentedrone Metabolite

Drug Testing and Analysis, Volume 18, Issue 4, Page 530-536, April 2026.
The paper describes an investigation related to the pentedrone norephedrine metabolite. The athlete's sample was analyzed using ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). According to the literature, this metabolite may originate from pentedrone, α‐pyrrolidinopentiophenone (PVP), or N‐ethylpentedrone (NEP).
D. Kwiatkowska, B. Peta, K. Grucza, A. Łabęcka, P. Konarski, K. Wojtkowiak, K. Grela, A. Sytniczuk, M. Wicka   +8 more
wiley   +1 more source

Supramolecular protecting groups can impart prosthetic stereoselectivity to catalytic systems employing unmodified achiral heterogenous catalysts. [PDF]

Chem Sci
Vergara-Arenas BI, Morales-Serna JA, Surman AJ.   +2 more
europepmc   +1 more source

Long‐Term Dynamics of the Geophyte Toxicoscordion fremontii (Torr.) Rydb. Across Two Wildfires: Fire‐Return Interval Implications

Ecology and Evolution, Volume 16, Issue 4, April 2026.
Our long‐term observations of the chaparral geophyte Toxicoscordion fremontii, over two decades and through two wildfires, provide information about its life history, while offering insights into potential impacts of altered fire regimes. These herbaceous perennials are long‐lived and flowered only after fires, which occurred decades apart.
Claudia M. Tyler, Mark I. Borchert
wiley   +1 more source