Results 171 to 180 of about 3,741,215 (311)

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Discovery of VU6083859, a TAOK1 Selective Inhibitor, and VU6080195, a <i>pan</i>-TAOK Activator. [PDF]

ACS Chem Neurosci
Schultz DC, Parr LC, Sweet H, Lamb S, Engers JL, Napier NC, McKinnie HG, Whomble D, Kramlinger V, Boutaud O, Lindsley CW.   +10 more
europepmc   +1 more source

Mechanistic Dichotomy in Enantioselective Pd‐Catalyzed Alkylation of Pyrroles With Diazoesters

European Journal of Organic Chemistry, EarlyView.
Ligand‐controlled mechanistic divergence controls the Pd‐catalyzed asymmetric alkylation of pyrroles with diazoesters. While bipyridine ligands promote a conventional metal‐carbene pathway, bipyridine‐N,N′‐dioxide ligands redirect catalysis through electrophilic CH metalation before carbene transfer.
Vladimir Yu. Vaganov, Yasuaki Fukazawa, Svyatoslav M. Pechenkin, Vladimir S. Hein, Aleksandr E. Rubtsov, Andrei V. Malkov   +5 more
wiley   +1 more source

Beyond the Solid Solution: Ordered Enantiomerically Unbalanced Packing in Surface-Confined Tetrahelicene Monolayers. [PDF]

Chirality
Cebrat A, Martin K, Mutombo P, Parschau M, Avarvari N, Ernst KH.   +5 more
europepmc   +1 more source

Diphenyl Disulfide‐Promoted Racemization of 1‐Arylethanols for Photobiocatalytic Dynamic Kinetic Resolution

European Journal of Organic Chemistry, EarlyView.
Purple‐light activation of aggregated diphenyl disulfide unlocks the photocatalyst‐free racemization of 1‐arylethanols. The resulting sulfur radical process operates under mild conditions and couples with the enzymatic acylation by Candida antarctica lipase B in a photobiocatalytic dynamic kinetic resolution, revealing new opportunities for sulfur ...
Cristina Guolo, Stefano Parisotto, Cristina Prandi   +2 more
wiley   +1 more source

Advances in Enantioselective Synthesis and Chiral Resolution of Insecticides. [PDF]

Molecules
López-Rosas CA, Delgado-Alvarado E, Barrera-Méndez F, Bonilla-Landa I, Olivares-Romero JL.   +4 more
europepmc   +1 more source

Asymmetric Synthesis of Tertiary α‐Aryl Stereocentres in Tetrahydro‐4H‐pyran‐4‐ones Using Pd‐Catalyzed Decarboxylative Asymmetric Protonation

European Journal of Organic Chemistry, EarlyView.
The Pd‐catalyzed decarboxylative asymmetric protonation (DAP) has been developed for sterically hindered tetrahydro‐4H‐pyran‐4‐one derived α‐aryl‐β‐keto esters. A substrate scope of nine examples of DAP showed that substrates containing a di‐ortho methoxy substitution pattern on the aryl ring gave rise to the highest enantioselectivities of up to 85 ...
Fionn McNeill, Joffrey Scriven, Fritz Bahns, Anugam V. Krishna, Julia Bruno‐Colmenarez, Patrick J. Guiry   +5 more
wiley   +1 more source

Double Salts and Racemate in Mefloquine-Ibuprofen and Mefloquine-Ketoprofen Systems. A Structural and Thermochemical Analysis. [PDF]

Chirality
Martins JB, Segatto JV, Tenorio JC, Carvalho PS.   +3 more
europepmc   +1 more source

π‐Extended Silyl Enolates as Emerging Platforms in Radical Chemistry

European Journal of Organic Chemistry, EarlyView.
This review covers the emerging role of π‐extended silyl polyenol ethers in radical chemistry. It highlights their versatile roles as electron‐rich SOMOphiles, silyl radical cation precursors, and nucleophilic partners in radical–polar crossover manifolds, while considering recent advances in photoredox catalysis, electrochemistry, and transition metal‐
Debora Guazzetti, Kelly Bugatti, Claudio Curti, Franca Zanardi   +3 more
wiley   +1 more source

Development and Characterization of a Noncovalent Stimulator of Interferon Genes Proteolysis-Targeting Chimeras. [PDF]

ChemMedChem
Hu B, Duerfeldt AS.
europepmc   +1 more source