Results 41 to 50 of about 770,200 (336)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Nematode Genome Announcement: Draft Genome of Meloidogyne chitwoodi, an Economically Important Pest of Potato in the Pacific Northwest

Molecular Plant-Microbe Interactions, 2021
Meloidogyne chitwoodi is one of the most devastating pests of potato in the U.S. Pacific Northwest (PNW). Nematode-infected tubers develop external as well as internal defects, making the potato tubers unmarketable, and resulting in economic losses ...
Sapinder Bali, Shengwei Hu, Kelly Vining, Chuck Brown, Hassan Mojtahedi, Lei Zhang, Cynthia Gleason, Vidyasagar Sathuvalli   +7 more
doaj   +1 more source

RACE AND INSANITY THE NEGRO RACE [PDF]

The Journal of Nervous and Mental Disease, 1885
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openaire   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Mechanical Running Power and Energy Expenditure in Uphill and Downhill Running

Sports
Trail running involves constant changes in terrain and slope, complicating the accurate assessment of energy expenditure during performance. This study aimed to examine the relationship between running power output (RPO), oxygen consumption (VO2), carbon
Fabrizio Gravina-Cognetti, Diego Chaverri, Antoni Planas, Jordi Montraveta, Marta Carrasco-Marginet, Silvia Puigarnau, Javier Espasa-Labrador, Xavier Iglesias   +7 more
doaj   +1 more source

Facial Contrast Is a Cross-Cultural Cue for Perceiving Age

Frontiers in Psychology, 2017
Age is a fundamental social dimension and a youthful appearance is of importance for many individuals, perhaps because it is a relevant predictor of aspects of health, facial attractiveness and general well-being.
Aurélie Porcheron, Aurélie Porcheron, Emmanuelle Mauger, Frédérique Soppelsa, Yuli Liu, Liezhong Ge, Olivier Pascalis, Richard Russell, Frédérique Morizot   +8 more
doaj   +1 more source

NH Congressional Races Remain Close 10/03/2012 [PDF]

, 2012
Democrats Carol Shea-Porter and Ann McLane Kuster have pulled ahead of incumbent Republicans Frank Guinta and Charlie Bass in races for New Hampshire’s two Congressional seats but both races are within the poll’s margin of sampling error.
Survey Center, UNH
core   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

IT SERVICE OF THE MODERNIZED GRAIN MOISTURIZING MACHINE

Zernovì Produkti ì Kombìkorma, 2021
The purpose of this work is to increase the efficiency of the grain humidifier, which is part of the system for preparing grain for grinding, ensuring the reliability of machines, its productivity, reducing energy consumption and improving the quality of
O. Gaponyuk, A. Aleksashin, G. Goncharuk
doaj   +1 more source