Results 131 to 140 of about 22,846 (183)
Some of the next articles are maybe not open access.
Clinical method of testing radiation-sensitizing agents in squamous cell carcinoma
Cancer, 1963Squamous cell carcinomas of the oral cavity and oropharynx provide suitable material for the evaluation of combined chemotherapy and radiotherapy because the therapeutic results in the primary lesions and in the metastatic lesions to the neck nodes can be assayed by palpation and inspection.
G H, FLETCHER +5 more
openaire +2 more sources
Effect of Radiation-Sensitizing Agents in Radiation Therapy of Mouse Mammary Carcinoma
Radiology, 1970IUdR, injected intraperitoneally, did not cause cell death for tumor cells proliferating as small colonies in subcutaneous tissues. Only a small amount of TdR of total DNA was replaced. A small fraction of the cells seemed to be in active cell proliferation, and they efficiently utilized the injected IUdR.
H D, Suit, R, Hewitt, M, Urano
openaire +2 more sources
International Journal of Radiation Oncology*Biology*Physics, 1989
Radiosensitization of hypoxic V79 Chinese hamster cells by 0.5 mM misonidazole at approximately 0-4 degrees C is substantially enhanced by pretreating the cells overnight with 0.1 mM buthionine sulfoximine, which lowers the cellular glutathione content to 5% of control values (from 4 mM to approximately 0.2 mM).
C J, Koch, C C, Stobbe, P, Hettiaratchi
openaire +2 more sources
Radiosensitization of hypoxic V79 Chinese hamster cells by 0.5 mM misonidazole at approximately 0-4 degrees C is substantially enhanced by pretreating the cells overnight with 0.1 mM buthionine sulfoximine, which lowers the cellular glutathione content to 5% of control values (from 4 mM to approximately 0.2 mM).
C J, Koch, C C, Stobbe, P, Hettiaratchi
openaire +2 more sources
Radiation sensitivity of bacteria and virus in porcine xenoskin for dressing agent
Radiation Physics and Chemistry, 2012Abstract In this study, gamma irradiation sensitivities of bacteria and viruses in porcine skin were evaluated to establish the optimum sterilization condition for the dressing material and a xenoskin graft. Escherichia coli and Bacillus subtilis were used as model pathogens and inoculated at 106–107 log CFU/g.
Eu-Ri Jo +3 more
openaire +1 more source
Journal of Clinical Oncology, 2015
TPS2078 Background: Post-resected glioblastoma multiforme (GMB) patients were treated with dodecafluoropentane emulsion (DDFPe) to evaluate the pharmacokinetics (PK), safety and potential survival ...
Jason D. Lickliter +6 more
openaire +1 more source
TPS2078 Background: Post-resected glioblastoma multiforme (GMB) patients were treated with dodecafluoropentane emulsion (DDFPe) to evaluate the pharmacokinetics (PK), safety and potential survival ...
Jason D. Lickliter +6 more
openaire +1 more source
Journal of Medicinal Chemistry, 1991
In view of the in vivo demonstrated radiation-potentiating activities of several previously studied 2,2-dimethylphosphoraziridines, six new compounds incorporating the bis(2,2-dimethyl-1-aziridinyl)phosphinyl moiety, together with an electron-affinic group such as 2-nitroimidazole or nitrobenzyl, have been synthesized and tested (1) in vitro for ...
M E, Perlman +7 more
openaire +3 more sources
In view of the in vivo demonstrated radiation-potentiating activities of several previously studied 2,2-dimethylphosphoraziridines, six new compounds incorporating the bis(2,2-dimethyl-1-aziridinyl)phosphinyl moiety, together with an electron-affinic group such as 2-nitroimidazole or nitrobenzyl, have been synthesized and tested (1) in vitro for ...
M E, Perlman +7 more
openaire +3 more sources
Enhancement of Alkylating Agent Cytotoxicity by Radiation Sensitizers
1986Animal tumors having a wide range of growth rates and histologies have been shown to contain hypoxic cells (1), which largely determine the radiation dose necessary for tumor control. Nonetheless, the nearly universal presence of hypoxic cells in solid tumors in rodents does not prove that the same is true of human tumors.
J. Martin Brown +3 more
openaire +1 more source
Radiation Research, 1968
Dose-survival curves of four strains of E. coli-B/r her- try-, Bs-1, B/r CSH, and 15T-were obtained in the presence and in the absence of non-toxic levels of several thiol-binding agents-N-ethylmaleimide (NEM), iodoacetamide (IA), and hydroxymercuribenzoate (HMB). The degree of radiosensitization by these agents was estimated from the increase in slope
H, Moroson, D N, Tenney
openaire +2 more sources
Dose-survival curves of four strains of E. coli-B/r her- try-, Bs-1, B/r CSH, and 15T-were obtained in the presence and in the absence of non-toxic levels of several thiol-binding agents-N-ethylmaleimide (NEM), iodoacetamide (IA), and hydroxymercuribenzoate (HMB). The degree of radiosensitization by these agents was estimated from the increase in slope
H, Moroson, D N, Tenney
openaire +2 more sources
Radiation sensitivity modification by chemotherapeutic agents.
Cancer clinical trials, 1981Three chemotherapeutic agents, chlorambucil, mustargen, and BCNU-409962, being investigated for their possible clinical use in conjunction with radiation therapy have been shown in vitro to dramatically affect the characteristics of standard radiation survival curves (in V79 cells and spheroids).
F W, Hetzel +3 more
openaire +1 more source