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Radiation Damage in Chemical Crystallography [PDF]
Although crystals suffering radiation damage is a well-known and studied phenomena for macromolecular crystallography[1], as far as we are aware there appears to be no such published work relating to chemical crystallography. However, there are numerous anecdotal accounts of disintegrating crystals and resolution progressively dropping off that have ...
Horton, Peter N. +4 more
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Radiation Damage in Macromolecular Crystallography [PDF]
Radiation damage inflicted on macromolecular crystals during X-ray diffraction experiments remains a limiting factor for structure solution, even when samples are cooled to cryotemperatures (~100 K). Efforts to establish mitigation strategies are ongoing and various approaches, summarized below, have been investigated over the last 15 years, resulting ...
Garman, E, Weik, M
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Circ-CPSF1 Worsens Radiation-Induced Oxidative Stress Injury in Caenorhabditis elegans
Radioactive substances have been used in various aspects in daily life. However, high-energy radiation could cause environmental problems, which would damage the human body.
Jing Yuan +8 more
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Proton-induced DNA damage promotes integration of foreign plasmid DNA into human genome
High-risk human papillomaviruses (HPVs) cause virtually all cervical cancer cases and are also associated with other types of anogenital and oropharyngeal cancers. Normally, HPV exists as a circular episomal DNA in the infected cell.
Meghri Katerji +7 more
doaj +1 more source
Exposure to Low-Dose Radiation Enhanced the Antitumor Effect of a Dendritic Cell Vaccine
The unsatisfactory clinical efficacy of dendritic cell (DC)-based cancer vaccines prepared by conventional methods is partly due to their insufficient capacity for migration.
Sinian Wang +8 more
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Expert consensus on hematopoietic reconstruction strategies for radiation injury
Hematopoietic injury treatment is one of the main challenges in the treatment of radiation damage. In the face of mass casualty, how to make prompt and accurate diagnosis and evaluation for hematopoietic damage and then reconstitute hematopoiesis is of ...
Professional Committee of Military Radiation Medicine +1 more
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FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair
The Fanconi anemia (FA) pathway is critically involved in the maintenance of hematopoietic stem cells and the suppression of carcinogenesis. A key FA protein, FANCD2, is monoubiquitinated and accumulates in chromatin in response to DNA interstrand ...
Junya Unno +11 more
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Germ cells are thought to exhibit a unique DNA damage response that differs from that of somatic stem cells, and previous studies suggested that Trp53 is not involved in the survival of spermatogonial stem cells (SSCs) after irradiation.
Kei Ishii +6 more
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Radiation-induced damage is a common occurrence in cancer patients who undergo radiotherapy. In this setting, radiation-induced damage can be refractory because the regeneration responses of injured tissues or organs are not well stimulated.
Xiaoyu Pu +5 more
doaj +1 more source
The aim of this work was to study the mechanisms of polymorphic transformations in ZrO2 ceramics under irradiation with heavy ions, as well as to determine the nature of structural distortions in the case of t-ZrO2 → c-ZrO2 type transformations and ...
Artem L. Kozlovskiy +2 more
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