Results 31 to 40 of about 2,871,612 (244)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Microgravity alleviates low-dose radiation-induced non-targeted carcinogenic effects
npj MicrogravityThe main hazards astronauts face in space collectively affect their health, especially increasing the carcinogenesis risk. However, it is still unclear how these hazards, especially microgravity and space radiation, induce the carcinogenic transformation
Yunan Ding +7 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
, 2021 This is a study concerning the use of Machine Learning (ML) techniques to ascertain the impacts of particle ionizing radiation (IR) on cell survival and DNA damage.
Dimitris Papakonstantinou +5 more
core +1 more source
X-ray-Induced Heating in the Vicinity of the X-ray Interaction Point
Applied Sciences, 2023 When X-rays pass through a material, radiation damage occurs, and heat is generated at the X-ray interaction point, which can then be transferred around the X-ray irradiation site. This X-ray-induced heat transfer can affect the temperature of the sample
Jangwoo Kim, Ki Hyun Nam
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Nanoscale X-Ray Diffraction of Silk Fibers
Frontiers in Materials, 2019 This report focuses on current possibilities and perspectives of scanning X-ray nanodiffraction for probing nanoscale heterogeneities in silk fibers such as nanofibrils, skin-core morphologies, nanocrystalline inclusions and fine fibers down to submicron
Christian Riekel +2 more
doaj +1 more source
Radiation Damage of Polydimethylsiloxane and Polyimide by X-ray Free-Electron Laser
Applied Sciences, 2022 A crystal delivery system is essential in serial femtosecond crystallography experiments using an X-ray free-electron laser (XFEL). Investigating the XFEL-induced radiation damage to materials potentially applicable to sample delivery devices is vital ...
Keondo Lee +11 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Effect of SiC Radiation Damage on High Temperature Oxidation Resistance
Yuanzineng kexue jishu, 2022 Silicon carbide (SiC) materials have many excellent properties, especially high temperature oxidation resistance, radiation resistance and low reaction activity in the presence of water vapor.
SONG Jie;LIAO Qing;LI Bingsheng;FENG Zongkai;YANG Junyuan
doaj