Results 41 to 50 of about 892,147 (307)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Microgravity alleviates low-dose radiation-induced non-targeted carcinogenic effects

npj Microgravity
The main hazards astronauts face in space collectively affect their health, especially increasing the carcinogenesis risk. However, it is still unclear how these hazards, especially microgravity and space radiation, induce the carcinogenic transformation
Yunan Ding, Ying Xu, Xiaofei Wang, Miaomiao Zhang, Qi Zeng, Congchong Yan, Guangming Zhou, Wentao Hu   +7 more
doaj   +1 more source

Racemate Resolution of Alanine and Leucine on Homochiral Quartz, and Its Alteration by Strong Radiation Damage

Life, 2021
Homochiral proteins orchestrate biological functions throughout all domains of life, but the origin of the uniform l-stereochemistry of amino acids remains unknown.
Adrien D. Garcia, Cornelia Meinert, Friedrich Finger, Uwe J. Meierhenrich, Ewald Hejl   +4 more
doaj   +1 more source

Nature of Radiation-Induced Defects in Quartz

, 2015
Although quartz ($\rm \alpha$-form) is a mineral used in numerous applications wherein radiation exposure is an issue, the nature of the atomistic defects formed during radiation-induced damage have not been fully clarified.
Bauchy, Mathieu, Pignatelli, Isabella, Sant, Gaurav N., Wang, Bu, Yu, Yingtian   +4 more
core   +1 more source

Antagonizing CD105 enhances radiation sensitivity in prostate cancer. [PDF]

, 2018
Radiation therapy is the primary intervention for nearly half of the patients with localized advanced prostate cancer and standard of care for recurrent disease following surgery.
Andres, Allen, Angara, Bryan, Bhowmick, Neil A, Duong, Frank, Gottlieb, Roberta, Haldar, Subhash, Liu, Zhenqiu, Madhav, Anisha, Mishra, Rajeev, Zumsteg, Zachary S   +9 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of SiC Radiation Damage on High Temperature Oxidation Resistance

Yuanzineng kexue jishu, 2022
Silicon carbide (SiC) materials have many excellent properties, especially high temperature oxidation resistance, radiation resistance and low reaction activity in the presence of water vapor.
SONG Jie;LIAO Qing;LI Bingsheng;FENG Zongkai;YANG Junyuan
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

X-ray-Induced Heating in the Vicinity of the X-ray Interaction Point

Applied Sciences, 2023
When X-rays pass through a material, radiation damage occurs, and heat is generated at the X-ray interaction point, which can then be transferred around the X-ray irradiation site. This X-ray-induced heat transfer can affect the temperature of the sample
Jangwoo Kim, Ki Hyun Nam
doaj   +1 more source

Calculation of The Lifetimes of Thin Stripper Targets Under Bombardment of Intense Pulsed Ions

, 2007
The problems of stripper target behavior in the nonstationary intense particle beams are considered. The historical sketch of studying of radiation damage failure of carbon targets under ion bombardment is presented.
A. S. Lebedev, D. V. Fedoseev, J. Yntema, J. E. Field, S. G. Lebedev, V. N. Korobenko, Ya. Groshkovsky   +6 more
core   +2 more sources