Results 51 to 60 of about 8,550 (218)
Metals, 2020 Safe and long term operation of nuclear reactors is one of the most discussed challenges in nuclear power engineering. The radiation degradation of nuclear design materials limits the operational lifetime of all nuclear installations or at least ...
Vladimír Slugeň +5 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Protective effects of leaf juice of Brassica rapa on radio-damage of mouse
浙江大学学报. 农业与生命科学版, 2001 The protection and repair effects of Brassica rapa leaf juice on radio-damage mouse induced by 60Coγ-rays were studied with the methods of measuring hemogram of mice, classifying of WBC, measuring wieght of the spleens and chest glands, and the ...
QIAN Xiao-wei +4 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Nanomaterials, 2020 AlN-based ceramics have great prospects for use in the field of structural materials for reactors of the new generation of GenIV, as well as dosimetric and optical devices.
Artem L. Kozlovskiy +2 more
doaj +1 more source
Cumulative Radiation Damage and Cumulative Radiation Effect [PDF]
Acta Radiologica: Oncology, 1983 Different mathematical formulas capable of replacing CRE have been analyzed. The purpose was to develop an expression which would yield a value identical with CRE for regular treatment schedules, but would represent more clearly and more truthfully the radiation damage of tissue. This quantity has been called cumulative radiation damage (CRD). Its unit
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
FISH comets show that the salvage enzyme TK1 contributes to gene-specific DNA repair
Frontiers in Genetics, 2014 Thymidine kinase 1 (TK1) is a salvage enzyme that phosphorylates thymidine, imported from surrounding fluids, to create dTMP, which is further phosphorylated to the DNA precursor dTTP.
Stephen eDownes +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Effect of DNA Damage on the Development of Diabetes Mellitus due toIonizing Radiation Exposure
Academic Science JournalExposure to ionizing radiation destroys several biological processes by disturbing the membranes of cells and causing damage to DNA, proteins, and mitochondria.
Lina Al-jameel +4 more
doaj +1 more source