Results 81 to 90 of about 890,751 (309)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Native SAD is maturing

open access: yesIUCrJ, 2015
Native SAD phasing uses the anomalous scattering signal of light atoms in the crystalline, native samples of macromolecules collected from single-wavelength X-ray diffraction experiments.
John P. Rose   +2 more
doaj   +1 more source

Electron beam induced damage in PECVD Si3N4 and SiO2 films on InP [PDF]

open access: yes
Phosphorus rich plasma enhanced chemical vapor deposition (PECVD) of silicon nitride and silicon dioxide films on n-type indium phosphide (InP) substrates were exposed to electron beam irradiation in the 5 to 40 keV range for the purpose of ...
Dickman, John E.   +4 more
core   +1 more source

Precision Crystal Calorimeters in High Energy Physics: Past, Present and Future [PDF]

open access: yes, 2006
Precision crystal calorimeters traditionally play an important role in high energy physics experiments. In the last two decades, it faces a challenge to maintain its precision in a hostile radiation environment.
Zhu, Ren-Yuan
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Hybrid Plasma/Molecular-Dynamics Approach for Efficient XFEL Radiation Damage Simulations

open access: yesCrystals, 2020
X-ray free-electron laser pulses initiate a complex series of changes to the electronic and nuclear structure of matter on femtosecond timescales.
Alexander Kozlov   +2 more
doaj   +1 more source

Activation and radiation damage in the environment of hadron accelerators

open access: yes, 2013
A component which suffers radiation damage usually also becomes radioactive, since the source of activation and radiation damage is the interaction of the material with particles from an accelerator or with reaction products.
Kiselev, Daniela
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Solar cell radiation damage experiment [PDF]

open access: yes
Space environment radiation effects on solar cell ...

core   +1 more source

An Analytical Model of Radiation-Induced Charge Transfer Inefficiency for CCD Detectors

open access: yes, 2013
The European Space Agency's Gaia mission is scheduled for launch in 2013. It will operate at L2 for 5 years, rotating slowly to scan the sky so that its two optical telescopes will repeatedly observe more than one billion stars.
Crowley, Cian   +3 more
core   +1 more source

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